Gene test may help pick safer painkillers after surgery
NCT ID NCT05966129
First seen Mar 22, 2026 · Last updated Apr 26, 2026 · Updated 4 times
Summary
This study looked at whether testing people's genes before surgery can help doctors choose pain medicines that work better and are safer. About 1,600 adults and children having planned surgeries were randomly assigned to get either gene-guided pain treatment or standard care. The focus was on people whose bodies process certain opioids slowly, to see if personalized medicine reduces pain and opioid use after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Indiana University
Indianapolis, Indiana, 46202, United States
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Meharry Medical College
Nashville, Tennessee, 37208, United States
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Nashville General Hospital
Nashville, Tennessee, 37208, United States
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Nemours Children's Health System
Wilmington, Delaware, 19803, United States
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Nemours Children's Health System
Jacksonville, Florida, 32207, United States
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Nemours Children's Health System
Orlando, Florida, 32827, United States
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Sanford Health
Fargo, North Dakota, 58104, United States
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University of Florida - Gainesville
Gainesville, Florida, 32610, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
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