Experimental vaccine aims to stop rare eye cancer from returning
NCT ID NCT01983748
First seen Feb 01, 2026 · Last updated May 13, 2026 · Updated 14 times
Summary
This phase 3 trial tests a personalized vaccine made from a patient's own immune cells and tumor RNA to prevent uveal melanoma from coming back after surgery. The study includes 200 people with a high-risk genetic type (monosomy 3) and no signs of spread. Half receive the vaccine over 2 years, the other half are simply watched. The goal is to see if the vaccine improves survival and keeps the cancer away.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dept. of Dermatology, University Hospital
Erlangen, Bavaria, 90154, Germany
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Städtisches Klinikum
Dessau, 06847, Germany
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University Hospital Department of Ophtalmology
Erlangen, Bavaria, 91054, Germany
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University Hospital Department of Ophtalmology
Würzburg, Bavaria, 97080, Germany
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University Hospital Department of Ophtalmology
Essen, 45122, Germany
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University Hospital Department of Ophtalmology
Homburg/Saar, 66421, Germany
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University Hospital Department of Ophtalmology
Lübeck, 23538, Germany
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University Hospital Department of Ophtalmology
Tübingen, 72076, Germany
Conditions
Explore the condition pages connected to this study.