ADHD drug trial for 4-5 year olds halted early

NCT ID NCT06431256

Terminated Disease control Sponsor: Ironshore Pharmaceuticals and Development, Inc Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a long-acting form of methylphenidate (Ritalin) given in the evening to children aged 4-5 with ADHD. The goal was to see if it improved ADHD symptoms and was safe. However, the trial was stopped early and only enrolled 26 children, so we cannot draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: methylphenidate hydrochloride (extended-release capsules)
What this could lead to: If successful, this could provide a treatment option for managing ADHD symptoms in preschool-aged children.
What could go wrong: The study was terminated early with only 26 participants, so results are limited. It is unclear if the drug is safe or effective in this young age group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATTENTION DEFICIT HYPERACTIVITY DISORDER

Contacts and locations

Locations

Advanced Research Center, Inc.

Anaheim, California, 92805, United States
Alivation Research, LLC

Lincoln, Nebraska, 68526, United States
CenExel iResearch, LLC

Decatur, Georgia, 30030, United States
Clinical Neuroscience Solutions, Inc.

Jacksonville, Florida, 32256, United States
Clinical Neuroscience Solutions, Inc.

Orlando, Florida, 32801, United States
Clinical Neuroscience Solutions, Inc.

Memphis, Tennessee, 38119, United States
Coastal Pediatric Research

Summerville, South Carolina, 29486, United States
DelRicht Research

New Orleans, Louisiana, 70115, United States
Harmonex, Inc.

Dothan, Alabama, 36303, United States
Midwest Research Group

Saint Charles, Missouri, 63304, United States
South Florida Research

Miami Springs, Florida, 33166, United States
University of Cincinnati Health

Cincinnati, Ohio, 45219, United States
Vector Clinical Trials

Las Vegas, Nevada, 89128, United States

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