ADHD drug trial for 4-5 year olds halted early

NCT ID NCT06431256

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a long-acting form of methylphenidate (Ritalin) given in the evening to children aged 4-5 with ADHD. The goal was to see if it improved ADHD symptoms and was safe. However, the trial was stopped early and only enrolled 26 children, so we cannot draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

methylphenidate hydrochloride (extended-release capsules)

What this could lead to

If successful, this could provide a treatment option for managing ADHD symptoms in preschool-aged children.

What could go wrong

The study was terminated early with only 26 participants, so results are limited. It is unclear if the drug is safe or effective in this young age group.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Research Center, Inc.

    Anaheim, California, 92805, United States

  • Alivation Research, LLC

    Lincoln, Nebraska, 68526, United States

  • CenExel iResearch, LLC

    Decatur, Georgia, 30030, United States

  • Clinical Neuroscience Solutions, Inc.

    Jacksonville, Florida, 32256, United States

  • Clinical Neuroscience Solutions, Inc.

    Orlando, Florida, 32801, United States

  • Clinical Neuroscience Solutions, Inc.

    Memphis, Tennessee, 38119, United States

  • Coastal Pediatric Research

    Summerville, South Carolina, 29486, United States

  • DelRicht Research

    New Orleans, Louisiana, 70115, United States

  • Harmonex, Inc.

    Dothan, Alabama, 36303, United States

  • Midwest Research Group

    Saint Charles, Missouri, 63304, United States

  • South Florida Research

    Miami Springs, Florida, 33166, United States

  • University of Cincinnati Health

    Cincinnati, Ohio, 45219, United States

  • Vector Clinical Trials

    Las Vegas, Nevada, 89128, United States