Hospitals join forces to hunt down missed diagnoses
NCT ID NCT05747755
First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time
Summary
This study tests whether a group of hospitals can reduce diagnostic errors by sharing data, benchmarking performance, and collaborating on safety improvements. Researchers will track adult patients on general medicine wards who die, are transferred to the ICU, or trigger a rapid response, and then adjudicate whether a diagnostic error occurred. The goal is to understand the causes of these errors and develop sustainable approaches that hospitals, clinicians, and patients can use together to prevent harm.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ADEPT Program, a behavioral intervention integrating diagnostic error surveillance, benchmarking, mentoring, and safety interventions into hospital care
- What this could lead to
- If successful, this could establish a practical model for hospitals to reduce diagnostic errors and improve patient safety.
- What could go wrong
- This is an early-stage, multi-site study, not a controlled trial of a drug. Results may vary across hospitals, and the intervention's impact on actual patient outcomes remains uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 7,200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients admitted to general medicine services at one of the participating hospitals and who either died during the hospitalization, were transferred to the ICU \>= 48 hours after admission, or had a rapid response. Exclusion Criteria: * Admitted for a non-medical reason * Patients coded in the field who are moribund on arrival to the hospital
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Brigham & Women's Hospital
RECRUITINGBoston, Massachusetts, 02120, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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