Gentle exercise shows promise for kids with brittle bones

NCT ID NCT04119388

Completed Symptom relief Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether a supervised, adapted exercise program can improve fitness and quality of life in children aged 6 to 18 with osteogenesis imperfecta, a rare genetic condition causing fragile bones. Thirty participants did 30-minute exercise sessions twice a week for a year. The main goal was to see if they could walk farther in six minutes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Adapted sports practices
What this could lead to: If it works, this could show that safe, tailored exercise helps children with brittle bones become more active and feel better.
What could go wrong: This is a small, completed study with only 30 participants. Results may not apply to all children with osteogenesis imperfecta, and benefits might be modest.

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Conditions

The condition(s) this trial relates to.

osteogenesis imperfecta

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOGENESIS IMPERFECTA

Contacts and locations

Locations

Centre de Référence des Maladies Rénales Rares - Hospices Civils de Lyon - Service de Néphrologie et Rhumatologie Pédiatriques - Hôpital Femme Mère Enfant

Bron, 69500, France

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