Adaptive dosing of immunotherapy shows promise for Tough-to-Treat liver cancer
NCT ID NCT07689175
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This trial investigates whether a combination of two immunotherapy drugs, nivolumab and ipilimumab, can control advanced liver cancer in patients with moderate cirrhosis (Child-Pugh B). The dosing is adjusted based on how each patient responds. The study aims to see how many patients achieve disease control, such as tumor shrinkage or stability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nivolumab and ipilimumab
- What this could lead to
- If successful, this could offer a new treatment option for people with advanced liver cancer and moderate cirrhosis who currently have few choices.
- What could go wrong
- This is a small, early-phase trial, so results may not apply broadly. Immunotherapy can cause serious side effects, including inflammation of organs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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