Smart brain pacemaker learns to adjust itself for Parkinson's patients

NCT ID NCT07682311

First seen Jul 02, 2026 ยท Last updated Jul 02, 2026

Summary

This study tests a new automated method to fine-tune adaptive deep brain stimulation (aDBS) for people with Parkinson's disease. aDBS uses brain signals to adjust stimulation in real time, but setting it up is complex. The trial will compare automated aDBS to standard continuous DBS in 40 adults aged 25-75 who already have a Medtronic Percept DBS device. The goal is to see if the automated approach reduces bothersome movement symptoms and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
adaptive deep brain stimulation (aDBS) using the Medtronic Percept device
What this could lead to
If successful, this could make adaptive DBS easier to set up and more effective for people with Parkinson's, potentially reducing daily movement problems and improving quality of life.
What could go wrong
This is a small, early-stage study (40 people) testing a new automated tuning method. It may not work for everyone, and the benefits seen here might not hold up in larger, longer-term trials.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94107, United States

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