Brain pacemaker showdown: which target tames Parkinson's best?

NCT ID NCT07250685

First seen Dec 16, 2025 · Last updated May 16, 2026 · Updated 17 times

Summary

This study compares two types of deep brain stimulation (DBS) for Parkinson's disease: one targeting the subthalamic nucleus (STN) and the other the globus pallidus internus (GPi). About 86 adults aged 22-75 with advanced Parkinson's will receive both treatments in a random order, and doctors will measure motor symptom improvement after 90 days. The goal is to find which target works better for controlling movement problems.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital Affiliated to Capital Medical University

    Beijing, Beijing Municipality, 100070, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Changhai Hospital of Shanghai

    Shanghai, Shanghai Municipality, 200120, China

  • Nanjing Brain Hospital

    Nanjing, Jiangsu, 210029, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • The First Affiliated Hospital of Dalian Medical University

    Dalian, Liaoning, 116011, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China

    Contact

  • Tianjin Huanhu Hospital

    Tianjin, Tianjin Municipality, 300350, China

    Contact

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China

Conditions

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