Brain pacemaker showdown: which target best eases Parkinson's symptoms?

NCT ID NCT07250685

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two brain areas for deep brain stimulation (DBS) in 86 people with Parkinson's disease. The goal is to see which target—the subthalamic nucleus (STN) or the globus pallidus internus (GPi)—better improves movement symptoms 90 days after surgery. Participants will be randomly assigned to one target and then switch to the other, with doctors and patients unaware of which is active.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital Affiliated to Capital Medical University

    Beijing, Beijing Municipality, 100070, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Changhai Hospital of Shanghai

    Shanghai, Shanghai Municipality, 200120, China

  • Nanjing Brain Hospital

    Nanjing, Jiangsu, 210029, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • The First Affiliated Hospital of Dalian Medical University

    Dalian, Liaoning, 116011, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China

    Contact

  • Tianjin Huanhu Hospital

    Tianjin, Tianjin Municipality, 300350, China

    Contact

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China