New drug aims to stop breast cancer return in High-Risk patients

NCT ID NCT07242352

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether the drug elacestrant can help prevent breast cancer from coming back in people with high-risk HR+/HER2- early breast cancer. About 1,520 participants will receive either elacestrant or standard hormone therapy for up to 7.5 years. The study compares how long people live without their cancer returning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Elacestrant (a hormone therapy drug)

What this could lead to

If successful, this could offer a more effective hormone therapy option for people with high-risk early breast cancer, potentially reducing the chance of cancer returning.

What could go wrong

This is a large Phase 3 trial, but results are not yet known. Elacestrant may not prove better than current treatments, and side effects are possible. The study is still recruiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brustzentrum Niederrhein, Johanniter Bethesda Krankenhaus

    RECRUITING

    Mönchengladbach, North Rhine-Westphalia, 41061, Germany

    Contact

    Contact

    Contact