New registry follows PAH patients on orenitram in Real-World settings

NCT ID NCT03045029

Ongoing Disease control Sponsor: United Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is a patient registry that follows 300 adults with pulmonary arterial hypertension (PAH) who are starting or recently started Orenitram. Researchers will track how well patients tolerate the drug and how it affects their daily function and symptoms over 78 weeks. The goal is to understand real-world use and side effects, not to test a new treatment.

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Conditions

The condition(s) this trial relates to.

pulmonary arterial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY ARTERIAL HYPERTENSION

Contacts and locations

Locations

AdventHealth Orlando

Orlando, Florida, 32803, United States
Albany Medical College

Albany, New York, 12208, United States
AnMed Health Pulmonary and Sleep Medicine

Anderson, South Carolina, 29621, United States
Aurora Denver Cardiology Associates

Aurora, Colorado, 80012, United States
Baylor University Medical Center

Dallas, Texas, 75246, United States
Beaumont Hospital Troy

Troy, Michigan, 48085, United States
Carilion Clinic

Roanoke, Virginia, 24014, United States
Center for Biomedical Research

Knoxville, Tennessee, 37919, United States
Central Florida Pulmonary Group, P.A.

Orlando, Florida, 32803, United States
Chest Medicine Associates

South Portland, Maine, 04106, United States
Cleveland Clinic Florida

Weston, Florida, 33331, United States
Harbor UCLA Medical Center

Torrance, California, 90502, United States
Heart Care Associates, LLC

Milwaukee, Wisconsin, 53215, United States
Houston Methodist Research Institute

Houston, Texas, 77030, United States
INTEGRIS Nazih Zuhdi Transplant Institution

Oklahoma City, Oklahoma, 73112, United States
Lima Memorial Hospital

Lima, Ohio, 45804, United States
Loyola University Chicago

Chicago, Illinois, 60153, United States
Lung Associates PA

Bradenton, Florida, 34208, United States
Mclaren Greater Lansing

Okemos, Michigan, 48864, United States
New York Methodist Hospital

Brooklyn, New York, 11215, United States
Northwell Health- Long Island Jewish Forest Hills

New Hyde Park, New York, 11040, United States
Oregon Health & Science University (OHSU)

Portland, Oregon, 97239, United States
Paloma Medical Group

San Juan Capistrano, California, 92675, United States
Piedmont Healthcare/Research

Austell, Georgia, 30309, United States
Pinehurst Medical Clinic, INC.

Pinehurst, North Carolina, 28374, United States
Pueblo Pulmonary Associates

Pueblo, Colorado, 81003, United States
Pulmonary Health Physicians, PC

Fayetteville, New York, 13066, United States
Renovatio Clinical

The Woodlands, Texas, 77380, United States
Saint Vincent Hospital and Health Services

Indianapolis, Indiana, 46260, United States
Santa Barbara Pulmonary Associates

Santa Barbara, California, 93105, United States
St. Vincent's Lung, Sleep, and Critical Care Specialists

Jacksonville, Florida, 33204, United States
Stony Brook University Medical Center

Islandia, New York, 11790, United States
USF South Florida Heart Health

Tampa, Florida, 33606, United States
University Of Iowa Hospital and Clinics

Iowa City, Iowa, 52242, United States
University of California - San Francisco

Fresno, California, 94143, United States
University of Florida Clinical Research Center

Gainesville, Florida, 32610, United States
University of Louisville Physicians Outpatient Center

Louisville, Kentucky, 40202, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of Pittsburgh - Heart and Vascular Medicine Institute

Pittsburgh, Pennsylvania, 15261, United States
University of Rochester

Rochester, New York, 14623, United States
University of Southern California - Keck Medical Center

Los Angeles, California, 90033, United States

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