Could a pill replace CPAP for sleep apnea? large study tests three treatments Head-to-Head
NCT ID NCT07679282
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study compares three treatments for obstructive sleep apnea: positive airway pressure (CPAP), a dental device that moves the jaw forward, and a combination of two medications (atomoxetine and oxybutynin). About 2,400 adults with sleep apnea will be randomly assigned to one of these treatments for one year. Researchers will track quality of life, side effects, and how well each treatment controls apnea episodes to find which option works best and is easiest for people to stick with.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
atomoxetine-oxybutynin
What this could lead to
If this trial succeeds, it could show that a simple pill works as well as CPAP or a dental device for treating sleep apnea, offering a more convenient option for many patients.
What could go wrong
The medication combination is not yet approved for sleep apnea, and side effects may limit its use. The study is also large but results may not apply to everyone with the condition.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Banner University Medical Center Tucson
Tucson, Arizona, 85719, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
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Stanford Medical Center
Palo Alto, California, 94305, United States
Contact
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University of Maryland Medical Center
Baltimore, Maryland, 21201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
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University of Miami Miller School of Medicine
Miami, Florida, 33136, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••