New hope for Tough-to-Treat lung cancer: testing different doses of promising drug

NCT ID NCT05853575

Recruiting now Disease control Sponsor: Mirati Therapeutics Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing two different dosing schedules of the drug adagrasib to see which one works better for people with advanced lung cancer that has a specific genetic change called KRAS G12C. It is for patients whose cancer has continued to grow after trying standard chemotherapy and immunotherapy. The main goal is to see how many patients' tumors shrink and to compare the safety of the two dosing plans.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

A.C. Camargo Cancer Center
RECRUITING

São Paulo, 01509-900, Brazil
A.C. Camargo Cancer Center
RECRUITING

São Paulo, 01509-900, Brazil

Contact Phone: •••-•••-••••

Contact Phone: •••-•••-••••
AP-HM Hopital Nord
RECRUITING

Marseille, Rhône, 13915, France

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Ankara City Hospital - Medical Oncology
RECRUITING

Ankara, 06800, Turkey (Türkiye)

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Ankara Liv Hospital
RECRUITING

Ankara, 06680, Turkey (Türkiye)

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Anthoni van Leeuwenhoek Ziekenhuis, Nederlands Kanker Instit
RECRUITING

Amsterdam, North Holland, 1066 CX, Netherlands

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Assuta Medical Center
RECRUITING

Tel Aviv, Tel Aviv, 64239, Israel

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Attikon Hospital - 2nd Critical Care
RECRUITING

Haidari - Athens, Pella, 12462, Greece

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Azienda Ospedaliero-Universitaria Maggiore Della Carita
RECRUITING

Novara, Piedmont, 28100, Italy

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Azienda Sanitaria Territoriale Pesaro Urbino (AST PU)
RECRUITING

Pesaro, Pesaro E Urbino, 61122, Italy

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Bnai Zion Medical Center Rheumatology Unit
RECRUITING

Haifa, Tel Aviv, 31048, Israel

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CHU de Grenoble
RECRUITING

Grenoble, Auvergne-Rhône-Alpes, 0, France

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CHU de Nantes - HÃ´pital Nord LaÃ"nnec (HGRL) - Service dOncologie medicale â€" Unite dOncologie thoracique
RECRUITING

Nantes, Pays de la Loire Region, 44093, France

Contact Phone: •••-•••-••••
Centre Hospitalier Universitaire D' Angers Hôpital Larrey - PNEUMOLOGIE - Département de PNEUMOLOGIE
RECRUITING

Angers, Maine-et-Loire, 49933, France

Contact Phone: •••-•••-••••
Centre Hospitalier Universitaire de Nice
RECRUITING

Nice, Provence-Alpes-Côte d'Azur Region, 06000, France

Contact Phone: •••-•••-••••
Centre Hospitalier Universitaire de Poitiers - Service d'oncologie Médicale Oncologie Medicale - Cancerolo
RECRUITING

Poitiers, Poitou-Charentes, 86000, France

Contact Phone: •••-•••-••••
Centre Hospitalier de Cornouaille
RECRUITING

Quimper, 29000, France

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Centre Hosptalier De Villefranche-Sur-Saone - Oncologie Medicale - Cancerolo
RECRUITING

Villefranche-sur-Saône, Rhône, 69655, France

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Centre Hôspitalier de Bretagne Sud - Hôpital du Scorff
RECRUITING

Lorient, 56322, France

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Centrul de Oncologie Euroclinic
RECRUITING

Iași, 700106, Romania

Contact Phone: •••-•••-••••
Centrul de Oncologie Sf Nectarie - Medical Oncology
RECRUITING

Craiova, Dolj, 200746, Romania

Contact Phone: •••-•••-••••
Chang Gung Medical Foundation - Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsuing City, Kaohsiung, 833401, Taiwan

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China Medical University Hospital - Internal Medicine
RECRUITING

Taichung, Taichung, 404327, Taiwan
China Medical University Hospital - Internal Medicine
RECRUITING

Taichung, Taichung, 404327, Taiwan

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Contact
Chung Shan Medical University Hospital - Internal Medicine
RECRUITING

Taichung, Taichung, 402306, Taiwan

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Clinica de Neoplasias Litoral
RECRUITING

Itajaí, Santa Catarina, 88301-220, Brazil

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Complejo Hospitalario Universitario De Santiago - Oncología Médica
RECRUITING

Santiago de Compostela, A Coruña, 15706, Spain

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Dr Abdurrahman Yurtaslan Training and Research Hospital - Medical Oncology
RECRUITING

Ankara, 06200, Turkey (Türkiye)

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Ege University Medical Faculty - Pulmonary
RECRUITING

Izmir, 35100, Turkey (Türkiye)

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Ehime University Hospital
RECRUITING

Tōon, Ehime, 791-0295, Japan

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Ensino e Terapia de Inovação Clinica AMO-ÉTICA / Ética Pesquisa e Ensino
RECRUITING

Salvador, Estado de Bahia, 41950-640, Brazil

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GIE Groupe hospitalier Paris Saint-Joseph/Vinci
RECRUITING

Paris, 75014, France

Contact Phone: •••-•••-••••
General Hospital Of Thessaloniki Papageorgiou
RECRUITING

Thessaloniki, 56429, Greece

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General Hospital of Athens "Alexandra"
RECRUITING

Athens, Attica, 11528, Greece

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Goztepe SuleymanYalcin Sehir Hast
RECRUITING

Istanbul, 34722, Turkey (Türkiye)

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Gülhane Eğitim ve Araştırma Hastanesi
RECRUITING

Ankara, Etlik/Ankara, 06010, Turkey (Türkiye)

Contact Phone: •••-•••-••••
Holistic Center for Cancer Study and Care
RECRUITING

Songkhla, 90110, Thailand

Contact Phone: •••-•••-••••
Hopital Haut-Leveque - Maladies respiratoires
RECRUITING

Pessac, Gironde, 33604, France

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Hospital Clinico Universitario De Valencia - Oncologia Médica y Hematologia
RECRUITING

Valencia, 46010, Spain

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Hospital Clínico San Carlos
RECRUITING

Madrid, 28040, Spain

Contact Phone: •••-•••-••••
Hospital General Universitario Gregorio Marañón
RECRUITING

Madrid, 28007, Spain

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Hospital Regional Universitario De Málaga
RECRUITING

Málaga, Andalusia, 29010, Spain

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Hospital Universitari Dexeus Grupo Quironsalud
RECRUITING

Barcelona, 08028, Spain

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Hospital Universitario Son Espases
RECRUITING

Palma de Mallorca, Balearic Islands, 07120, Spain

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Hospital Universitario Vall d'Hebron - Oncología Médica
RECRUITING

Barcelona, 08035, Spain

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Hospital Universitario Virgen de la Macarena - Oncología Médica
RECRUITING

Seville, 41009, Spain

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Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08025, Spain

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Hôpital Bégin - Service d'Oncologie
RECRUITING

Saint-Mandé, 94163, France

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IEO - Istituto Europeo di Oncologia, IRCCS
RECRUITING

Milan, 20141, Italy

Contact Phone: •••-•••-••••
Institut de Cancerologie de I'Ouest - Service d'Oncologie Medicale - Service d'Oncologie Médicale
RECRUITING

Saint-Herblain, Loire-Atlantique, 44800, France

Contact Phone: •••-•••-••••
Istanbul Oncology Hospital - Medical Oncology
RECRUITING

Istanbul, Samsun, 34846, Turkey (Türkiye)

Contact Phone: •••-•••-••••
Istituto Nazionale Tumori Regina Elena - IRCCS - IFO
RECRUITING

Roma, 00144, Italy

Contact Phone: •••-•••-••••
Istituto di Candiolo, IRCCS
RECRUITING

Candiolo, Torino, 10060, Italy

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Kansas City VA Hospital
RECRUITING

Kansas City, Missouri, 64128, United States

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Klinički bolnički centar Sestre milosrdnice
RECRUITING

Zagreb, City of Zagreb, 10000, Croatia

Contact Phone: •••-•••-••••
Local Institution - 101
COMPLETED

Santa Rosa, California, 95403, United States
Local Institution - 103
WITHDRAWN

Minneapolis, Minnesota, 55417, United States
Local Institution - 104
WITHDRAWN

Chicago, Illinois, 60607, United States
Local Institution - 125
NOT_YET_RECRUITING

Toluca, 50090, Mexico

Contact
Local Institution - 127
NOT_YET_RECRUITING

Colonia Roma, Mexico City, 06760, Mexico

Contact
Local Institution - 128
WITHDRAWN

Tuxtla Gutiérrez, Chiapas, 29064, Mexico
Local Institution - 129
NOT_YET_RECRUITING

Colonia Nápoles, Mexico City, 3810, Mexico

Contact
Local Institution - 151
WITHDRAWN

Surquillo, Lima region, 15038, Peru
Local Institution - 152
WITHDRAWN

San Martín de Porres, Lima region, 15102, Peru
Local Institution - 326
COMPLETED

Seoul, Seoul Teugbyeolsi [Seoul-T'ukp, 08308, South Korea
Local Institution - 328
COMPLETED

Seoul, Seoul Teugbyeolsi [Seoul-T'ukp, 06273, South Korea
Local Institution - 351
WITHDRAWN

Kaohsiung City, Kaohsiung, 824005, Taiwan
Local Institution - 354
WITHDRAWN

Taipei City, Taipei, 112201, Taiwan
Local Institution - 355
WITHDRAWN

Taichung, Taichung, 407219, Taiwan
Local Institution - 375
COMPLETED

Khon Kaen, 40002, Thailand
Local Institution - 376
COMPLETED

Muang, Chiang Mai, 50200, Thailand
Local Institution - 377
COMPLETED

Bangkok, Krung Thep Maha Nakhon [Bangko, 10700, Thailand
Local Institution - 400
COMPLETED

Osaka, Ôsaka [Osaka], 541-8567, Japan
Local Institution - 403
COMPLETED

Nishinomiya, Hyôgo [Hyogo], 663-8501, Japan
Local Institution - 525
WITHDRAWN

Pula, Istria County, 52100, Croatia
Local Institution - 577
COMPLETED

Pátrai, Achaïa, 265 04, Greece
Local Institution - 582
WITHDRAWN

Athens, Attica, 11528, Greece
Local Institution - 600
WITHDRAWN

Szolnok, Jász-Nagykun-Szolnok, H-5000, Hungary
Local Institution - 603
WITHDRAWN

Debrecen, H-4012, Hungary
Local Institution - 650
COMPLETED

Krakow, Lesser Poland Voivodeship, 30-727, Poland
Local Institution - 651
COMPLETED

Gdynia, Pomeranian Voivodeship, 81-519, Poland
Local Institution - 653
COMPLETED

Lublin, 20-064, Poland
Local Institution - 676
COMPLETED

Oviedo, Principality of Asturias, 33011, Spain
Local Institution - 679
COMPLETED

Madrid, 28033, Spain
Local Institution - 684
WITHDRAWN

Valencia, 46026, Spain
Local Institution - 686
WITHDRAWN

Santander, Cantabria, 39008, Spain
Local Institution - 689
WITHDRAWN

Barcelona, 08036, Spain
Local Institution - 703
WITHDRAWN

Istanbul, Samsun, 34846, Turkey (Türkiye)
Local Institution - 709
COMPLETED

Istanbul, Samsun, 34214, Turkey (Türkiye)
Local Institution - 726
WITHDRAWN

Bucharest, 022328, Romania
Local Institution - 727
WITHDRAWN

Craiova, Dolj, 200094, Romania
Local Institution - 750
WITHDRAWN

Kamenitz, Vojvodina, 21204, Serbia
Local Institution - 751
WITHDRAWN

Belgrade, 11070, Serbia
Local Institution - 753
WITHDRAWN

Belgrade, 11000, Serbia
Local Institution - 802
WITHDRAWN

Breda, North Brabant, 4818 CK, Netherlands
Medisprof - Medical Oncology
RECRUITING

Cluj-Napoca, Cluj, 400641, Romania

Contact Phone: •••-•••-••••
Memorial Ankara Hastanesi
RECRUITING

Ankara, Ankara/Cankaya, 06520, Turkey (Türkiye)

Contact
National Cancer Center
RECRUITING

Goyang-si, Gyeonggido [Kyonggi-do], 10408, South Korea

Contact Phone: •••-•••-••••
National Cancer Center Hospital East
RECRUITING

Kashiwa, Tiba [Chiba], 277-8577, Japan

Contact
Oncocenter- Oncologie Clinica - Medical Oncology
RECRUITING

Timișoara, Timiș County, 300166, Romania

Contact Phone: •••-•••-••••
Oncocentro Belo Horizonte
RECRUITING

Belo Horizonte, São Paulo, 30360-680, Brazil

Contact Phone: •••-•••-••••
Oncolab - Medical Oncology
RECRUITING

Craiova, Dolj, 200385, Romania

Contact Phone: •••-•••-••••
Ospedale S.Maria della Misericordia, AO di Perugia, Università degli Studi di Perugia
RECRUITING

Perugia, 6132, Italy

Contact Phone: •••-•••-••••
Ovidius Clinical Hospital
RECRUITING

Ovidiu, Constanța County, 905900, Romania

Contact Phone: •••-•••-••••
Rambam Health Care Campus
RECRUITING

Haifa, 3109601, Israel

Contact
Samsung Medical Center
RECRUITING

Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], 6351, South Korea

Contact
Shaare Zedek Medical center
RECRUITING

Jerusalem, Jerusalem, 9103102, Israel

Contact Phone: •••-•••-••••
Sigmedical Services S.R.L.
RECRUITING

Suceava, 720214, Romania

Contact Phone: •••-•••-••••
Specijalna Bolnica Medico - Rijeka
RECRUITING

Rijeka, Primorje-Gorski Kotar County, 51000, Croatia

Contact Phone: •••-•••-••••
Spitalul Clinic Judetean De Urgenta Sibiu
RECRUITING

Sibiu, 550245, Romania

Contact Phone: •••-•••-••••
St. Antonius Hospital
RECRUITING

Utrecht, 3543 AZ, Netherlands

Contact
St. Luke's Hospital S.A.
RECRUITING

Panórama, 552 36, Greece

Contact
Tel Aviv Sourasky Medical Center - Oncology - Hematology/Oncology
RECRUITING

Tel Aviv, 6423906, Israel

Contact Phone: •••-•••-••••
Theageneio Cancer Hospital
RECRUITING

Thessaloniki, 54639, Greece

Contact Phone: •••-•••-••••
Trakya Univ Hastanesi Ic Hastal
RECRUITING

Edirne, 22030, Turkey (Türkiye)

Contact Phone: •••-•••-••••
Uniao Brasileira de Educacao E Assistencia
RECRUITING

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil

Contact
University Clinical Center of Kragujevac, Center for Internal Oncology
RECRUITING

Kragujevac, Šumadijski Okrug, 34000, Serbia

Contact Phone: •••-•••-••••
University Clinical Center of Nis, Clinic for Pediatrics-Department for Pulmonology
RECRUITING

Nis, Vojvodina, 11000, Serbia

Contact
VA North Texas Healthcare System/Dallas VA Medical Center
RECRUITING

Dallas, Texas, 75216-7167, United States

Contact Phone: •••-•••-••••
Veterans Affairs Medical Center (VAMC) - Durham - Oncology
RECRUITING

Durham, North Carolina, 27705, United States

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

ADVANCED CANCER MALIGNANT NEOPLASM OF LUNG METASTATIC CANCER