Can needles calm Cycle-Linked migraines?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. meet the diagnostic criteria for MRM according to the ICHD-3, with a documented history of MRM for at least 12 months; 2. have a confirmed diagnosis of migraine by a neurologist; 3. aged 18-45 years; 4. have regular menstrual cycles (28 ± 7 days) with menstruation lasting 3-7 days; 5. have experienced ≥3 headache days during each menstrual cycle (days -2 to +3) and ≥5 total headache days per cycle over the past 3 months and baseline period; migraine attacks must last 4-72 hours without acute medication, or at least 2 hours when treated; 6. have completed a headache diary during the screening period (covering at least one full menstrual cycle), demonstrating good compliance; 7. headache diary data during screening period must meet the ICHD-3 criteria for MRM and fulfill criteria (4) and (5); 8. voluntarily sign the informed consent. Exclusion Criteria: 1. irregular menstrual cycles, defined as cycle length outside the range of 28±7 days or menstruation duration \<3 days or \>7 days; 2. presence of secondary headache disorders, facial neuralgia, or cranial neuralgia; 3. combined with serious primary diseases such as cardiovascular, hepatic, renal, gastrointestinal, or hematological disorders that may interfere with the treatment protocol, or comorbid neurological conditions such as epilepsy, parkinson's disease, or other central nervous system disorders; 4. headache symptoms caused by other conditions, such as moderate to severe head or neck trauma, perimenstrual infections, intracranial tumors, intracranial infections, endocrine or metabolic disorders; 5. receipt of preventive treatment for headache within 1 month prior to the screening visit; 6. afraid of needles or received acupuncture treatment within 3 months; 7. unwillingness to undergo the study intervention or failure to sign the informed consent.