Acne pills may reshape your gut and skin bacteria

NCT ID NCT07544251

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how two common acne antibiotics, sarecycline and doxycycline, change the bacteria living in your gut and on your skin. Researchers will track these changes in 30 people with acne over the treatment period. The goal is to understand which antibiotic is gentler on your body's natural bacterial balance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sarecycline and doxycycline
What this could lead to
If successful, this could help doctors choose acne treatments that minimize disruption to beneficial bacteria.
What could go wrong
This is a small, early-phase study with only 30 participants, so results may not apply broadly. It focuses on microbiome changes, not directly on acne improvement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Integrative Research Institute

    RECRUITING

    Sacramento, California, 95819, United States

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