New study probes muscle fibrosis in swallowing disorder
NCT ID NCT04641702
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how muscle scarring in the esophagus relates to swallowing problems in people with achalasia. Researchers will use a special probe and muscle biopsies to measure scarring and muscle function. The goal is to better understand the disease so doctors can treat it earlier.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Atropine
What this could lead to
If successful, this could lead to earlier diagnosis and better treatments for achalasia by linking muscle scarring to esophageal function.
What could go wrong
This is an early-phase observational study with only 80 participants, so results may not apply to all patients. The atropine challenge may cause temporary side effects like dry mouth or blurred vision.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Emory Saint Joseph's Hospital
RECRUITINGAtlanta, Georgia, 30342, United States
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States