Which patch keeps the carotid artery open longer?

NCT ID NCT01184183

First seen Aug 18, 2026 ยท Last updated Aug 18, 2026

Summary

This trial compares two types of patches used to close the artery after carotid endarterectomy, a surgery that removes blockages in the neck artery to prevent stroke. The Accuseal patch, a newer synthetic option, is tested against the Bovine Pericardial patch, which has been used for decades. The goal is to see which patch better reduces bleeding during surgery, lowers the risk of stroke, and prevents the artery from narrowing again over time. The study includes patients with significant carotid artery narrowing, whether they have had symptoms or not.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Two surgical patches used to close the artery after carotid endarterectomy: the Accuseal patch (a synthetic material) and the Bovine Pericardial patch (made from cow tissue).
What this could lead to
If the Accuseal patch works better, it could reduce the risk of stroke and keep the carotid artery open longer after surgery, improving long-term outcomes for patients.
What could go wrong
This is a single-center trial with 200 patients, so results may not apply broadly. The Accuseal patch might have a longer bleeding time, and long-term benefits are not yet proven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vascular Center of Excellence

    Charleston, West Virginia, 25304, United States

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