Major trial tests promising new drug for common adult leukemia

NCT ID NCT04008706

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, global study aimed to understand the safety and effectiveness of the drug acalabrutinib for adults with chronic lymphocytic leukemia (CLL). It included over 550 people, including those newly diagnosed, those whose cancer returned, and those who had taken a similar drug before. Participants took the pill twice daily for up to four years to see how well it controlled their cancer and what side effects occurred.

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Contacts and locations

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Locations

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Chandler, Arizona, 85224, United States
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Long Beach, California, 90806, United States
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Redlands, California, 92373, United States
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Whittier, California, 90603, United States
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Fort Myers, Florida, 33908, United States
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Jacksonville, Florida, 32256, United States
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St. Petersburg, Florida, 33705, United States
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Marietta, Georgia, 30060, United States
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Normal, Illinois, 61761, United States
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Peoria, Illinois, 61615, United States
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Fort Wayne, Indiana, 46845, United States
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Indianapolis, Indiana, 46260, United States
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Shreveport, Louisiana, 71105, United States
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Saint Cloud, Minnesota, 56303, United States
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Kansas City, Missouri, 64132, United States
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Bethlehem, Pennsylvania, 18015, United States
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Chattanooga, Tennessee, 37404, United States
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Nashville, Tennessee, 37203, United States
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Dallas, Texas, 75235, United States
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Adelaide, 5000, Australia
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Bedford Park, 5042, Australia
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Clayton, 3168, Australia
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Fitzroy, 3065, Australia
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Nedlands, 6009, Australia
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South Brisbane, 4101, Australia
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Belo Horizonte, 30130-100, Brazil
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Curitiba, 81520-060, Brazil
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Goiânia, 74605-020, Brazil
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Porto Alegre, 90035-003, Brazil
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Porto Alegre, 90110-270, Brazil
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Ribeirão Preto, 14048-900, Brazil
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São Paulo, 01236-030, Brazil
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São Paulo, 01323-900, Brazil
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Calgary, Alberta, T2N 4N2, Canada
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Edmonton, Alberta, T6G 1Z2, Canada
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Victoria, British Columbia, V8R 6V5, Canada
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Winnipeg, Manitoba, R3E 0V9, Canada
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Halifax, Nova Scotia, B3H 1V7, Canada
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Brampton, Ontario, L6R 3J7, Canada
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Newmarket, Ontario, L3Y 2P9, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Aalborg, 9100, Denmark
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Aarhus, 8200, Denmark
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Herlev, 2730, Denmark
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København Ø, 2100, Denmark
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Odense, 5000, Denmark
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Roskilde, 4000, Denmark
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Hus, 00029, Finland
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Kuopio, 70210, Finland
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Tampere, 33521, Finland
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Bordeaux, 33076, France
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Brest, 29609, France
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Limoges, 87042, France
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Reims, 51092, France
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Tours, 37000, France
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Vandœuvre-lès-Nancy, 54511, France
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Bayern, 63739, Germany
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Essen, 45147, Germany
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Homburg, 66421, Germany
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Porta Westfalica, 32457, Germany
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Schwäbisch Hall, 74523, Germany
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Catanzaro, 88100, Italy
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Milan, 20122, Italy
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Roma, 00161, Italy
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Roma, 00168, Italy
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Siena, 53100, Italy
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Arnhem, 6815 AD, Netherlands
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Dordrecht, 3318 AT, Netherlands
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Utrecht, 3584 CX, Netherlands
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Bergen, 5053, Norway
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Oslo, 1478, Norway
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Trondheim, 7006, Norway
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Moscow, 115478, Russia
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Moscow, 125167, Russia
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Moscow, 125284, Russia
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Nizhny Novgorod, 603126, Russia
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Petrozavodsk, 185019, Russia
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Saint Petersburg, 191024, Russia
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Saint Petersburg, 194291, Russia
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Saint Petersburg, 197022, Russia
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Saint Petersburg, 197110, Russia
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Saint Petersburg, 197341, Russia
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Smolensk, 214015, Russia
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Smolensk, 214031, Russia
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Syktyvkar, 167904, Russia
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Busan, 49241, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06591, South Korea
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Seoul, 135-710, South Korea
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Ulsan, 44033, South Korea
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Barcelona, 08036, Spain
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Madrid, 28006, Spain
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Madrid, 28041, Spain
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Marbella, 29603, Spain
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Ourense, 32005, Spain
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Oviedo, 33011, Spain
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Vitoria-Gasteiz, 01009, Spain
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Zaragoza, 50009, Spain
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Luleå, 97180, Sweden
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Lund, 221 85, Sweden
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Uppsala, 75185, Sweden
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Taichung, 40705, Taiwan
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Tainan, 704, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 11217, Taiwan
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Liverpool, L7 8XP, United Kingdom
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Newmarket, CB8 7XN, United Kingdom

Conditions

Explore the condition pages connected to this study.

CHRONIC LYMPHOCYTIC LEUKEMIA