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One shot to restore hearing? new drug takes on steroids

NCT ID NCT05776459

Ongoing Disease control Sponsor: AudioCure Pharma GmbH Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single injection of a new drug called AC102 into the ear, comparing it to standard steroid pills for sudden hearing loss. About 210 adults with hearing loss in one ear will take part. The goal is to see if the injection improves hearing better than steroids, with fewer side effects.

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Conditions

The condition(s) this trial relates to.

Ear Diseases hearing loss disorder Hearing Loss, Sensorineural Hearing Loss, Unilateral otorhinolaryngologic disease sensorineural hearing loss disorder sudden sensorineural hearing loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEARING LOSS, SENSORINEURAL

Contacts and locations

Locations

  • ALL-MED Cetrum Medyczne

    Lodz, 94-046, Poland

  • Centrum Medyczne Kwiatowa

    Bydgoszcz, 85-047, Poland

  • Centrum Medyczne MAVIT - Szpital Specjalistyczny Katowice

    Katowice, 40-431, Poland

  • Clinical Hospital Centar "dr Dragisa Misovic-Dedinje"

    Belgrade, 11040, Serbia

  • Clinical Hospital Centre Zvezdara

    Belgrade, 11050, Serbia

  • Clinical-Hospital Center Zemun

    Belgrade, 11080, Serbia

  • Communal non-profit enterprise "Central city clinical hospital of Ivano-Frankivsk city council"

    Ivano-Frankivsk, 76018, Ukraine

  • Evangelisches Krankenhaus - Universitätsklinik für HNO

    Oldenburg, 26122, Germany

  • Fakultní nemocnice v Motole

    Prague, 150 06, Czechia

  • HNO-Praxis Eidelstedter Platz

    Hamburg, 22523, Germany

  • Heilig Geist Hospital

    Bensheim, 64625, Germany

  • Johannes Weseling Clinic Minden

    Minden, 32429, Germany

  • Kliniczny Szpital Wojewódzki Nr 1 im. Fryderyka Chopina w Rzeszowie

    Rzeszów, 35-055, Poland

  • Klinik für Hals-, Nasen- und Ohrenheilkunde am Universitätsklinikum

    Jena, 07747, Germany

  • Klinik für Hals-, Nasen-, Ohrenheilkunde - Charité Campus Benjamin Franklin - HNO Hochschulambulanz

    Berlin, 10117, Germany

  • Klinik und Poliklinik für Hals-, Nasen-, Ohrenkrankheiten, Kopf- und Halschirurgie

    Greifswald, 17475, Germany

  • Klinikum rechts der Isar

    München, 81675, Germany

  • LLC Clinic of Healthy Family Astramed

    Uzhhorod, 88000, Ukraine

  • MC Universal Clinic Oberig of Kapytal LLC

    Kyiv, 03057, Ukraine

  • Military Medical Academy - ENT department

    Belgrade, 11040, Serbia

  • Municipal non-profit enterprise Oleksandrivska clinical hospital of Kyiv of the executive body of Kyiv city council

    Kyiv, 01601, Ukraine

  • Municipal non-profit enterprise Regional Clinical Hospital of Ivano-Frankivsk Regional Council

    Ivano-Frankivsk, 76000, Ukraine

  • Oddział Laryngologii

    Opole, 45-418, Poland

  • Ordensklinikum Linz GmbH Barmherzige Schwestern

    Linz, 4010, Austria

  • Pardubická nemocnice, Klinika ORL a chirurgie hlavy a krku

    Pardubice, 532 03, Czechia

  • SRH Zentralklinikum Suhl GmbH

    Suhl, 98527, Germany

  • Trialmed

    Warsaw, 02-482, Poland

  • Unfallkrankenhaus Berlin

    Berlin, 12683, Germany

  • University Clinical Centre of Serbia

    Belgrade, 11000, Serbia

  • University Hospital Dresden 'Carl Gustav Carus' - HNO

    Dresden, 01307, Germany

  • Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde

    Graz, 8036, Austria

  • Universitätsklinik für Hals-, Nasen- und Ohrenkrankheiten

    Vienna, 1090, Austria

  • Universitätsklinik für Hals-Nasen-Ohren-Krankheiten

    Salzburg, 5020, Austria

  • Universitätsklinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie

    Halle, 06120, Germany

  • Universitätsklinikum HNO

    Würzburg, 97080, Germany

  • Universitätsklinikum Regensburg - Klinik für HNO-Heilkunde

    Regensburg, 93053, Germany

  • Universitätsmedizin der Johannes Gutenberg Universität Mainz Hals-, Nasen-, Ohrenklinik und Poliklinik

    Mainz, 51131, Germany

  • Uniwersytecki Szpital Kliniczny Nr 1

    Szczecin, 71-252, Poland

  • Zdravotnická zařízení Olomouc, ORL

    Olomouc, 779 00, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.