New drug shows promise for bipolar depression in early trial

NCT ID NCT06869187

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding a new drug called ABX-002 to current treatments can improve depression symptoms in adults with bipolar disorder. About 30 people with bipolar depression will take the drug for 6 weeks, and some will have brain scans to see how it affects brain chemistry. The goal is to find a better way to ease depressive episodes.

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Conditions

The condition(s) this trial relates to.

bipolar depression bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Autobahn Site #201

    Cromwell, Connecticut, 06416, United States

  • Autobahn Site #203

    Brooklyn, New York, 11235, United States

  • Autobahn Site #204

    Staten Island, New York, 10314, United States

  • Autobahn Site #205

    Marlton, New Jersey, 08053, United States

  • Autobahn Site #207

    New York, New York, 10016, United States

  • Autobahn Site #208

    Cherry Hill, New Jersey, 08002, United States

  • Autobahn Site #209

    Hamilton, New Jersey, 08690, United States

  • Autobahn Site #210

    Hartford, Connecticut, 06106, United States

  • Autobahn Site #211

    New York, New York, 10019, United States

  • Autobahn Site #212

    Miami, Florida, 33014, United States

  • Autobahn Site #213

    Walnut Creek, California, 94596, United States

  • Autobahn Site #214

    Bellevue, Washington, 98007, United States

  • Autobahn Site #215

    Chicago, Illinois, 60622, United States

  • Autobahn Site #216

    Worcester, Massachusetts, 01608, United States