New hope for liver cancer: targeted drug ABSK-011 enters phase 2 trial

NCT ID NCT07327034

Recruiting now Disease control Sponsor: Abbisko Therapeutics Co, Ltd Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called ABSK-011 for people with advanced liver cancer that has not responded to prior treatments. The drug targets a specific protein (FGF19) found in some tumors. About 141 participants will receive either ABSK-011 plus standard care or a placebo plus standard care to see if the drug helps shrink tumors or slow cancer growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ABSK-011
What this could lead to: If it works, this could offer a new treatment option for people with advanced liver cancer who have a specific genetic marker (FGF19 overexpression).
What could go wrong: This is an early Phase 2 trial with only 141 participants, so results may not apply to everyone. The drug may not shrink tumors or improve survival, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATOCELLULAR CARCINOMA (HCC)

Contacts and locations

Locations

Affiliated Cancer Hospital of Harbin Medical University
RECRUITING

Harbin, Heilongjiang, China
Affiliated Hospital ofJining Medical University
RECRUITING

Jining, Shandong, China
Anhui Provincial Cancer Hospital
RECRUITING

Hefei, Anhui, China
Beijing Tsinghua Changgung Hospital
RECRUITING

Beijing, Beijing Municipality, China
Chongqing university cancer hospital
RECRUITING

Chongqing, Chongqing Municipality, China
Eastern hepatobilliary surgery hospital
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, China
First Affiliated Hospital of Gannan Medical University
RECRUITING

Ganzhou, Jiangxi, China
First Hospital of Shanxi Medical University
RECRUITING

Taiyuan, Shanxi, China
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, Shanghai Municipality, China
Fujian Cancer Hospital
RECRUITING

Fuzhou, Fujian, China
General Hospital of Easten Theater Command
NOT_YET_RECRUITING

Nanjing, Jiangsu, China
General Hospital of Ningxia Medical University
RECRUITING

Yinchuan, Ningxia, China
Guangxi Medical University Cancer Hospital
RECRUITING

Nanning, Guangxi, China
Guizhou Provincial People's Hospital
RECRUITING

Guiyang, Guizhou, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, China
Hubei Cancer Hospital
RECRUITING

Wuhan, Hubei, China
Hunan Cancer Hospital
RECRUITING

Changsha, Hunan, China
Hunan Cancer Hospital
RECRUITING

Changsha, Hunan, China
Jiangxi Cancer Hospital
RECRUITING

Nanchang, Jiangxi, China
Jilin Cancer Hospital
RECRUITING

Changchun, Jilin, China
Liaoning Cancer Hospital
RECRUITING

Shenyang, Liaoning, China
Liuzhou People's Hospital
RECRUITING

Liuzhou, Guangxi, China
Mianyang Central Hospital
RECRUITING

Mianyang, Sichuan, China
Nanjing Tianyinshan Hospital
RECRUITING

Nanjing, Jiangsu, China
Nantong Tumor Hospital
RECRUITING

Nantong, Jiangsu, China
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, China
Renji Hospital,Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, Shanghai Municipality, China
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, China
Shanxi Cancer Hospital
RECRUITING

Taiyuan, Shanxi, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, China
Sun Yat-sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, China
The Affiliated Hospital of Xuzhou Medical University
RECRUITING

Xuzhou, Jiangsu, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, China
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Henan University of Science & Technology
RECRUITING

Luoyang, Henan, China
The First Affiliated Hospital of USTC
RECRUITING

Hefei, Anhui, China
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi’an, Shanxi, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, China
The First Affiliated Hospital with NanJing Medical University
RECRUITING

Nanjing, Jiangsu, China
The First Hospital of China Medical University
RECRUITING

Shenyang, Liaoning, China
The First Hospital of Jilin University
RECRUITING

Changchun, Jilin, China
The Second Affiliated Hospital Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, China
The Second Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, China
The Second Affiliated Hospital of Guilin Medical University
RECRUITING

Guilin, Guangxi, China
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, China
TianJin Cancer Hospital Airport Hospital
RECRUITING

Tianjin, Tianjin Municipality, China
Tongji Hospital
RECRUITING

Wuhan, Hubei, China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, China
West China Hospital of Sichuan University
RECRUITING

Chengdu, Sichuan, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, China
Zhongshan Hospital, Fudan University
RECRUITING

Shanghai, Shanghai Municipality, China

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