New eye drug aims to offer cheaper option for blinding disease

NCT ID NCT07614776

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 29, 2026 · Updated 6 times

Summary

This phase 3 trial tests whether a new drug called ABP 938 works as well as the approved treatment Eylea HD for wet age-related macular degeneration, a leading cause of vision loss. About 304 people aged 50 and older with untreated wet AMD will receive injections of either drug into the eye. The main goal is to see if vision improvement is similar between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ABP 938 (a biosimilar of aflibercept) and aflibercept (Eylea HD)
What this could lead to: If successful, this could provide a more affordable treatment option for wet age-related macular degeneration, helping preserve vision.
What could go wrong: This is a similarity study, not a new cure. Even if ABP 938 works as well as Eylea HD, it still requires regular eye injections and does not restore lost vision.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nemaline myopathy wet macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NAMD NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Advanced Research, LLC
RECRUITING

Pensacola, Florida, 32503, United States
Associated Vitreoretinal and Uveitis Consultants
RECRUITING

Carmel, Indiana, 46032, United States
Austin Retina Associates - Ophthalmology/Retina
RECRUITING

Austin, Texas, 78705, United States
California Eye Specialists Medical Group, Inc
RECRUITING

Pasadena, California, 91107, United States
California Retina Consultants
RECRUITING

Santa Barbara, California, 93103, United States
Charleston Neuroscience Institute
RECRUITING

Charleston, South Carolina, 29414-5896, United States
Emerson Clinical Research- Virginia Retina Specialists
RECRUITING

Falls Church, Virginia, 22042-2349, United States
Medeye Associates - Research
RECRUITING

Miami, Florida, 33143, United States
Mid Atlantic Retina Specialists
RECRUITING

Hagerstown, Maryland, 21740-5846, United States
Mississippi Retina Assoc
RECRUITING

Madison, Mississippi, 39110, United States
NC Retina Associates-RCA
RECRUITING

Wake Forest, North Carolina, 27587, United States
Ophthalmic Consultants of Long Island - Research
RECRUITING

Oceanside, New York, 11572, United States
Palmetto Retina Center - Main (RCA)
RECRUITING

Columbia, South Carolina, 29169, United States
Palmetto Retina Center, Florence (RCA)
RECRUITING

West Columbia, South Carolina, 29169, United States
Retina Associates
RECRUITING

Elmhurst, Illinois, 60126, United States
Retina Associates of Utah - Retina Specialist
RECRUITING

Salt Lake City, Utah, 84107, United States
Retina Center NW PLLC
RECRUITING

Silverdale, Washington, 98383, United States
Retina Consultants of Minnesota
RECRUITING

Edina, Minnesota, 55435, United States
Retina Consultants of Orange County
RECRUITING

Fullerton, California, 92835-3432, United States
Retina Consultants of South Carolina, Charleston Neuroscience Institute- Ladson (RCA)
RECRUITING

Ladson, South Carolina, 29456, United States
Retina Consultants of South Carolina, Charleston Neuroscience institute - Blufffon (RCA)
RECRUITING

Beaufort, South Carolina, 29902, United States
Retina Consultants of Southern Colorado (Colorado Springs)- RCA
RECRUITING

Colorado Springs, Colorado, 80909-1183, United States
Retina Consultants of Southwest Florida - Naples
RECRUITING

Naples, Florida, 34103-4457, United States
Retina Consultants of Texas - Katy Retina Center
RECRUITING

Houston, Texas, 77401, United States
Retina Consultants of Texas - Schertz
RECRUITING

Schertz, Texas, 78154, United States
Retina Group of New England
RECRUITING

Waterford, Connecticut, 06385, United States
Retina Specialists
RECRUITING

Towson, Maryland, 21204, United States
Retinal Consultants Medical Group, Inc - Sacramento - Parkcenter Drive (RCA)
RECRUITING

Sacramento, California, 95825, United States
Retinal Consultants Medical Group, Inc.-Sacramento, Greenback Lane, (RCA)
RECRUITING

Modesto, California, 95356, United States
South Coast Retina Center - RCA
RECRUITING

Long Beach, California, 90607, United States
Texas Retina Associates (TRA) - Arlington
RECRUITING

Arlington, Texas, 76012, United States
Texas Retina Associates (TRA) - Dallas Main
RECRUITING

Dallas, Texas, 75231, United States
Texas Retina Associates - Fort Worth
RECRUITING

Fort Worth, Texas, 76104, United States
The Retina Institute, Research Retina Institute (RCA)
RECRUITING

St Louis, Missouri, 63128, United States
Vision Research Center Eye Associates of New Mexico
RECRUITING

Albuquerque, New Mexico, 87109, United States
Vitreoretinal Associates of Washington
RECRUITING

Bellevue, Washington, 98004-3779, United States

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