New MS drug candidate ABP 692 goes Head-to-Head with ocrevus in major trial

NCT ID NCT06700343

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study tests whether a new drug called ABP 692 works as well as the approved drug Ocrevus for people with relapsing-remitting multiple sclerosis (RRMS). About 444 adults with RRMS will receive either ABP 692 or Ocrevus to compare how the drugs move through the body and how well they reduce new brain lesions seen on MRI. The goal is to show ABP 692 is similar to Ocrevus in effectiveness and safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

ARENSIA Clinics
RECRUITING

Bucharest, 011658, Romania
ARENSIA Exploratory Medicine at County Hospital Cluj-Napoca
RECRUITING

Cluj-Napoca, 400006, Romania
Aarhus Universitetshospital, Skejby
RECRUITING

Aarhus N, Central Jutland, 8200, Denmark
Academic Specialist Center
COMPLETED

Stockholm, SE113 65, Sweden
Advanced Neurosciences Research, Llc
RECRUITING

Fort Collins, Colorado, 80528, United States
Algemeen Ziekenhuis Delta
RECRUITING

Roeselare, West-Vlaanderen, 8800, Belgium
Aqualane Clinical Research
RECRUITING

Naples, Florida, 34105, United States
Arencia Exploratory Medicine
RECRUITING

Kyiv, 01135, Ukraine
Bellaria-Maggiore Hospital-Azienda USL Bologna
RECRUITING

Bologna, 40139, Italy
Casa di Cura Privata del Policlinico Igea S.p.A
RECRUITING

Milan, 20144, Italy
Centre Hospitalier Universitaire de Nimes (CHU) - Hopital Universitaire Caremeau
RECRUITING

Nîmes, 30029, France
Centrum Medyczne Neuroprotect
RECRUITING

Warsaw, 01-684, Poland
Centrum Neurologii Krzysztof Selmaj
RECRUITING

Lodz, 90-324, Poland
Clinic of Neurology, University Clinical Center Nis
RECRUITING

Niš, 18000, Serbia
Clinical Endpoints, LLC
RECRUITING

Scottsdale, Arizona, 85258, United States
Clinical Hospital Center Zvezdara
RECRUITING

Belgrade, 11000, Serbia
Curiositas-ad-Sanum GmbH
RECRUITING

Ebersberg, 85560, Germany
Dansk Multipel Sklerose Center
RECRUITING

Glostrup Municipality, 2600, Denmark
Diagnostic Consultative Center Convex Ltd
RECRUITING

Sofia, Sofiiska, 1680, Bulgaria
Emerald Coast Neurology/Synergy Clinical Research
RECRUITING

Pensacola, Florida, 32504, United States
Fakultna Nemocnica Trnava
RECRUITING

Trnava, 91775, Slovakia
Fakultni Nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 05, Czechia
Fakultni nemocnice u sv. Anny v Brne
RECRUITING

Brno, 656 91, Czechia
Foothills Medical Centre
RECRUITING

Calgary, Alberta, T2N 2T9, Canada
Froedtert Hospital-Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Hackensack Meridian Health
RECRUITING

Paramus, New Jersey, 07652, United States
Hasbani Neurology
RECRUITING

New Haven, Connecticut, 06511, United States
Hawaii Pacific Neuroscience
RECRUITING

Honolulu, Hawaii, 96817, United States
Henry Ford Health
RECRUITING

Detroit, Michigan, 48202, United States
Hope Neurology
RECRUITING

Knoxville, Tennessee, 37922, United States
Hospital Alvaro Cunqueiro
RECRUITING

Vigo, 36312, Spain
Hospital Clinic de Barcelona - Institut Clinic de Malalties Hematologiques i Oncologiques (ICMHO)
RECRUITING

Barcelona, 08036, Spain
Hospital General Universitario Gregorio Maranon (HGUGM)
RECRUITING

Madrid, 28007, Spain
Hospital Regional Universitario de Malaga
RECRUITING

Málaga, 29010, Spain
Hospital Santa Caterina
RECRUITING

Salt, 17190, Spain
Hospital Universitario Doctor Peset
RECRUITING

Valencia, 46017, Spain
Hospital Universitario Fundacion Alcorcon
RECRUITING

Alcorcón, 28922, Spain
Hospital Universitario de Torrejon
RECRUITING

Torrejón de Ardoz, 28850, Spain
Hospital Vithas Nisa Sevilla
RECRUITING

Castilleja de la Cuesta, 41950, Spain
Hospital of Lithuanian University of Health Sciences Kaunas
RECRUITING

Kaunas, 50161, Lithuania
JFK Medical Center
RECRUITING

Edison, New Jersey, 08820, United States
Jo Ann University Hospital
RECRUITING

Tbilisi, 0159, Georgia
Klaipedas University Hospital
RECRUITING

Klaipėda, LT-92288, Lithuania
Klinische Forschung Hamburg GmbH
RECRUITING

Hamburg, 20253, Germany
Knight Neurology
RECRUITING

Rockledge, Florida, 32955, United States
Krakowska Akademia Neurologii
RECRUITING

Krakow, 31-505, Poland
LTD Pineo Medical Ecosystem
RECRUITING

Tbilisi, 0114, Georgia
Lone Star Neurology
RECRUITING

Frisco, Texas, 75035, United States
MA-LEK Clinical Sp. z o.o.
RECRUITING

Katowice, Silesian Voivodeship, 40-571, Poland
MS Center Research Unit, Sahlgrenska University Hospital
RECRUITING

Gothenburg, 413 45, Sweden
MS-Netwerk Limburg - Revalidatie & MS Centrum
RECRUITING

Overpelt, 3900, Belgium
MTZ Clinical Research Powered by Pratia
RECRUITING

Warsaw, 02-172, Poland
Medical Center Hera EOOD
RECRUITING

Sofia, 1510, Bulgaria
Michigan Institute For Neurological Disorders (Glendale Neurological Associates) - Farmington Hills
RECRUITING

Farmington, Michigan, 48334-2979, United States
Mountain Neurological Research Center
RECRUITING

Basalt, Colorado, 81621, United States
Multipel Studies Institut fuer klinische Studien GbR
RECRUITING

Hamburg, 22179, Germany
NDx Clinical Research, Inc
RECRUITING

Dayton, Ohio, 45459, United States
NZOZ Neuromed M. i M. Nastaj Sp.P
RECRUITING

Lublin, 20-064, Poland
Nemocnica Ruzinov-Univerzitna Nemocnica Bratislava (UNB)
RECRUITING

Bratislava, 82626, Slovakia
Nemocnice Teplice
RECRUITING

Teplice, 415 01, Czechia
Neuro Medic Clinic
RECRUITING

Katowice, 40-686, Poland
Neuro-Care
RECRUITING

Katowice, Silesian Voivodeship, 40-749, Poland
Neurocentrum Bydgoszcz
RECRUITING

Bydgoszcz, 85-796, Poland
Neurologicka ambulancia Empathy, s.r.o.
RECRUITING

Bratislava, 85101, Slovakia
Neurology Offices of South Florida
RECRUITING

Boca Raton, Florida, 33428, United States
Neuropraxis Munchen Sud - Unterhaching
RECRUITING

Unterhaching, 82008, Germany
Nzoz Neuro-Kard Ilkowski I Partnerzy Spolka Partnerska Lekarzy
RECRUITING

Poznan, 61-853, Poland
Ondokuz Mayis University Health Practice and Research Hospital
RECRUITING

Samsun, 55280, Turkey (Türkiye)
Ospedale Regionale di Lugano, Sede Civico
RECRUITING

Lugano, 6903, Switzerland
Ospedale Sant'Andrea Hospital
RECRUITING

Rome, 00189, Italy
Praxisgemeinschaft fuer Neurologie, Psychiatrie und Psychotherapie - Regensburg
COMPLETED

Regensburg, 93059, Germany
Premier Neurology, PC
RECRUITING

Greenville, South Carolina, 29650, United States
Premiere Research Institute Palm Beach
RECRUITING

West Palm Beach, Florida, 33407, United States
Privatni ordinace neurologie
RECRUITING

Hradec Králové, 50003, Czechia
Profound Research - Neurology Center of Southern California
RECRUITING

Carlsbad, California, 92011, United States
Regional Hospital Jihlava
RECRUITING

Jihlava, 58601, Czechia
Resmedica Sp. z o.o.
RECRUITING

Kielce, 25-726, Poland
Sestre milosrdnice University Hospital Center
RECRUITING

Zagreb, 10000, Croatia
Singlepoint Healthcare Opco, LLC
RECRUITING

Columbus, Ohio, 43235, United States
Studienzentrum Dr. Bischof GmbH
RECRUITING

Böblingen, 71034, Germany
Sydvestjysk Sygehus
RECRUITING

Esbjerg, Region Syddanmark, 6700, Denmark
The Ottawa Hospital Research Institute
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
Triad Neurological Associates
RECRUITING

Winston-Salem, North Carolina, 27103, United States
UMHAT Dr.Georgi Stranski EAD
RECRUITING

Pleven, 5800, Bulgaria
UMHATEM N.I. Pirogov
RECRUITING

Sofia, 1606, Bulgaria
Uludag University Medical Faculty
RECRUITING

Bursa, 16059, Turkey (Türkiye)
Universidad de Sevilla - Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
Universita degli Studi della Campania Luigi Vanvitelli - Clinica Neurologia II - Centro Sclerosi Mul
RECRUITING

Naples, 80138, Italy
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
Universitaetsklinikum Leipzig
RECRUITING

Leipzig, 04103, Germany
Universitaetsspital Bern - Inselspital
RECRUITING

Bern, 3010, Switzerland
Universitat de Valencia - Hospital Universitari i Politecnic La Fe de Valencia (Hospital La Fe Bulev
RECRUITING

Valencia, 46026, Spain
University Clinical Centre of Kragujevac
RECRUITING

Kragujevac, 34000, Serbia
University Hospital Carl Gustav Carus
RECRUITING

Dresden, 01307, Germany
University Hospital Centre Zagreb
RECRUITING

Zagreb, 10000, Croatia
University Medical Centre Ljubljana-UKCL
RECRUITING

Ljubljana, 1110, Slovenia
University Multi-Profile Hospital for Active Treatment (UMHAT) St. Ivan Rilski
RECRUITING

Sofia, 1431, Bulgaria
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of NM/Mind Imaging center
RECRUITING

Albuquerque, New Mexico, 87131, United States
University of South Alabama
RECRUITING

Mobile, Alabama, 36617, United States
Vanderbilt University Medical Center (VUMC)
RECRUITING

Nashville, Tennessee, 37215, United States
Vitamed Galaj i Cichomski sp.j.
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-079, Poland
Vithas Hospital Parque San Antonio
RECRUITING

Malag, 29016, Spain
Yeditepe University Kosuyolu Hospital
RECRUITING

Kadıköy, Istanbul, 34718, Turkey (Türkiye)
ZNS Siegen GmbH
RECRUITING

Siegen, 57076, Germany
Zentrum fur klinische Forschung Dr.Scholl
RECRUITING

Bad Homburg, 61348, Germany

Conditions

Explore the condition pages connected to this study.

RELAPSING-REMITTING MULTIPLE SCLEROSIS (RRMS)