New MS drug candidate ABP 692 faces off against ocrevus in major trial

NCT ID NCT06700343

Ongoing Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a new drug, ABP 692, works as well as the approved drug Ocrevus for people with relapsing-remitting multiple sclerosis (RRMS). About 152 adults with RRMS will receive either ABP 692 or Ocrevus to compare how the drugs move through the body and how well they reduce new brain lesions seen on MRI. The goal is to see if ABP 692 can be a similar, safe option for controlling MS.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RELAPSING-REMITTING MULTIPLE SCLEROSIS (RRMS)

Contacts and locations

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Locations

ARENSIA Clinics

Bucharest, 011658, Romania
ARENSIA Exploratory Medicine at County Hospital Cluj-Napoca

Cluj-Napoca, 400006, Romania
Aarhus Universitetshospital, Skejby

Aarhus N, Central Jutland, 8200, Denmark
Academic Specialist Center

Stockholm, SE113 65, Sweden
Advanced Neurosciences Research, Llc

Fort Collins, Colorado, 80528, United States
Algemeen Ziekenhuis Delta

Roeselare, West-Vlaanderen, 8800, Belgium
Aqualane Clinical Research

Naples, Florida, 34105, United States
Arencia Exploratory Medicine

Kyiv, 01135, Ukraine
Bellaria-Maggiore Hospital-Azienda USL Bologna

Bologna, 40139, Italy
Casa di Cura Privata del Policlinico Igea S.p.A

Milan, 20144, Italy
Centre Hospitalier Universitaire de Nimes (CHU) - Hopital Universitaire Caremeau

Nîmes, 30029, France
Centrum Medyczne Neuroprotect

Warsaw, 01-684, Poland
Centrum Neurologii Krzysztof Selmaj

Lodz, 90-324, Poland
Clinic of Neurology, University Clinical Center Nis

Niš, 18000, Serbia
Clinical Endpoints, LLC

Scottsdale, Arizona, 85258, United States
Clinical Hospital Center Zvezdara

Belgrade, 11000, Serbia
Curiositas-ad-Sanum GmbH

Ebersberg, 85560, Germany
Dansk Multipel Sklerose Center

Glostrup Municipality, 2600, Denmark
Diagnostic Consultative Center Convex Ltd

Sofia, Sofiiska, 1680, Bulgaria
Emerald Coast Neurology/Synergy Clinical Research

Pensacola, Florida, 32504, United States
Fakultna Nemocnica Trnava

Trnava, 91775, Slovakia
Fakultni Nemocnice Hradec Kralove

Hradec Králové, 500 05, Czechia
Fakultni nemocnice u sv. Anny v Brne

Brno, 656 91, Czechia
Foothills Medical Centre

Calgary, Alberta, T2N 2T9, Canada
Froedtert Hospital-Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Hackensack Meridian Health

Paramus, New Jersey, 07652, United States
Hasbani Neurology

New Haven, Connecticut, 06511, United States
Hawaii Pacific Neuroscience

Honolulu, Hawaii, 96817, United States
Henry Ford Health

Detroit, Michigan, 48202, United States
Hope Neurology

Knoxville, Tennessee, 37922, United States
Hospital Alvaro Cunqueiro

Vigo, 36312, Spain
Hospital Clinic de Barcelona - Institut Clinic de Malalties Hematologiques i Oncologiques (ICMHO)

Barcelona, 08036, Spain
Hospital General Universitario Gregorio Maranon (HGUGM)

Madrid, 28007, Spain
Hospital Regional Universitario de Malaga

Málaga, 29010, Spain
Hospital Santa Caterina

Salt, 17190, Spain
Hospital Universitario Doctor Peset

Valencia, 46017, Spain
Hospital Universitario Fundacion Alcorcon

Alcorcón, 28922, Spain
Hospital Universitario de Torrejon

Torrejón de Ardoz, 28850, Spain
Hospital Vithas Nisa Sevilla

Castilleja de la Cuesta, 41950, Spain
Hospital of Lithuanian University of Health Sciences Kaunas

Kaunas, 50161, Lithuania
JFK Medical Center

Edison, New Jersey, 08820, United States
Jo Ann University Hospital

Tbilisi, 0159, Georgia
Klaipedas University Hospital

Klaipėda, LT-92288, Lithuania
Klinische Forschung Hamburg GmbH

Hamburg, 20253, Germany
Knight Neurology

Rockledge, Florida, 32955, United States
Krakowska Akademia Neurologii

Krakow, 31-505, Poland
LTD Pineo Medical Ecosystem

Tbilisi, 0114, Georgia
Lone Star Neurology

Frisco, Texas, 75035, United States
MA-LEK Clinical Sp. z o.o.

Katowice, Silesian Voivodeship, 40-571, Poland
MS Center Research Unit, Sahlgrenska University Hospital

Gothenburg, 413 45, Sweden
MS-Netwerk Limburg - Revalidatie & MS Centrum

Overpelt, 3900, Belgium
MTZ Clinical Research Powered by Pratia

Warsaw, 02-172, Poland
Medical Center Hera EOOD

Sofia, 1510, Bulgaria
Michigan Institute For Neurological Disorders (Glendale Neurological Associates) - Farmington Hills

Farmington, Michigan, 48334-2979, United States
Mountain Neurological Research Center

Basalt, Colorado, 81621, United States
Multipel Studies Institut fuer klinische Studien GbR

Hamburg, 22179, Germany
NDx Clinical Research, Inc

Dayton, Ohio, 45459, United States
NZOZ Neuromed M. i M. Nastaj Sp.P

Lublin, 20-064, Poland
Nemocnica Ruzinov-Univerzitna Nemocnica Bratislava (UNB)

Bratislava, 82626, Slovakia
Nemocnice Teplice

Teplice, 415 01, Czechia
Neuro Medic Clinic

Katowice, 40-686, Poland
Neuro-Care

Katowice, Silesian Voivodeship, 40-749, Poland
Neurocentrum Bydgoszcz

Bydgoszcz, 85-796, Poland
Neurologicka ambulancia Empathy, s.r.o.

Bratislava, 85101, Slovakia
Neurology Offices of South Florida

Boca Raton, Florida, 33428, United States
Neuropraxis Munchen Sud - Unterhaching

Unterhaching, 82008, Germany
Nzoz Neuro-Kard Ilkowski I Partnerzy Spolka Partnerska Lekarzy

Poznan, 61-853, Poland
Ondokuz Mayis University Health Practice and Research Hospital

Samsun, 55280, Turkey (Türkiye)
Ospedale Regionale di Lugano, Sede Civico

Lugano, 6903, Switzerland
Ospedale Sant'Andrea Hospital

Rome, 00189, Italy
Praxisgemeinschaft fuer Neurologie, Psychiatrie und Psychotherapie - Regensburg

Regensburg, 93059, Germany
Premier Neurology, PC

Greenville, South Carolina, 29650, United States
Premiere Research Institute Palm Beach

West Palm Beach, Florida, 33407, United States
Privatni ordinace neurologie

Hradec Králové, 50003, Czechia
Profound Research - Neurology Center of Southern California

Carlsbad, California, 92011, United States
Regional Hospital Jihlava

Jihlava, 58601, Czechia
Resmedica Sp. z o.o.

Kielce, 25-726, Poland
Rush University Medical Center, Rush University Cancer Center

Chicago, Illinois, 60612-3841, United States
Sestre milosrdnice University Hospital Center

Zagreb, 10000, Croatia
Singlepoint Healthcare Opco, LLC

Columbus, Ohio, 43235, United States
Studienzentrum Dr. Bischof GmbH

Böblingen, 71034, Germany
Sydvestjysk Sygehus

Esbjerg, Region Syddanmark, 6700, Denmark
The Ottawa Hospital Research Institute

Ottawa, Ontario, K1H 8L6, Canada
Triad Neurological Associates

Winston-Salem, North Carolina, 27103, United States
UMHAT Dr.Georgi Stranski EAD

Pleven, 5800, Bulgaria
UMHATEM N.I. Pirogov

Sofia, 1606, Bulgaria
Uludag University Medical Faculty

Bursa, 16059, Turkey (Türkiye)
Universidad de Sevilla - Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Universita degli Studi della Campania Luigi Vanvitelli - Clinica Neurologia II - Centro Sclerosi Mul

Naples, 80138, Italy
Universitaetsklinikum Essen

Essen, 45147, Germany
Universitaetsklinikum Heidelberg

Heidelberg, 69120, Germany
Universitaetsklinikum Leipzig

Leipzig, 04103, Germany
Universitaetsspital Bern - Inselspital

Bern, 3010, Switzerland
Universitat de Valencia - Hospital Universitari i Politecnic La Fe de Valencia (Hospital La Fe Bulev

Valencia, 46026, Spain
University Clinical Centre of Kragujevac

Kragujevac, 34000, Serbia
University Hospital Carl Gustav Carus

Dresden, 01307, Germany
University Hospital Centre Zagreb

Zagreb, 10000, Croatia
University Medical Centre Ljubljana-UKCL

Ljubljana, 1110, Slovenia
University Multi-Profile Hospital for Active Treatment (UMHAT) St. Ivan Rilski

Sofia, 1431, Bulgaria
University of Kansas Medical Center

Kansas City, Kansas, 66160, United States
University of NM/Mind Imaging center

Albuquerque, New Mexico, 87131, United States
University of South Alabama

Mobile, Alabama, 36617, United States
Vanderbilt University Medical Center (VUMC)

Nashville, Tennessee, 37215, United States
Vitamed Galaj i Cichomski sp.j.

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-079, Poland
Vithas Hospital Parque San Antonio

Malag, 29016, Spain
Yeditepe University Kosuyolu Hospital

Kadıköy, Istanbul, 34718, Turkey (Türkiye)
ZNS Siegen GmbH

Siegen, 57076, Germany
Zentrum fur klinische Forschung Dr.Scholl

Bad Homburg, 61348, Germany