Could a gut bacteria byproduct tame MS?

NCT ID NCT07318129

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a daily supplement of indole-3-propionic acid (IPA), a substance naturally made by gut bacteria, can help people with relapsing-remitting multiple sclerosis (RRMS). Over 27 months, 220 adults will take either IPA or a placebo. The main goal is to see if IPA reduces disease activity, including relapses, brain lesions, and disability progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Indole-3-propionic acid (IPA), a natural gut bacteria byproduct, taken as a daily supplement

What this could lead to

If it works, this could point toward a simple dietary supplement that helps control MS disease activity and slow neurodegeneration.

What could go wrong

This is an early-stage trial with no phase designation, so results are uncertain. The supplement may not outperform placebo, and benefits may be modest.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Glostrup Hospital

    RECRUITING

    Glostrup Municipality, 2600, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••