Can your own cells fix your knee? new trial tests bone marrow and fat injections against placebo

NCT ID NCT05517434

Recruiting now Symptom relief Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a person's own bone marrow cells or a mix of fat cells and platelet-rich plasma into the knee can reduce pain from osteoarthritis. About 148 adults with moderate knee arthritis will receive either the real treatment or a placebo (salt water) injection. Researchers will track pain and function for 12 months to see if these natural cell treatments work better than a dummy shot.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS, KNEE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Toronto Western Hospital, University Health Network
RECRUITING

Toronto, Ontario, M5T 2S8, Canada
Women's College Hospital
NOT_YET_RECRUITING

Toronto, Ontario, M5S 1B2, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.