New CT algorithm aims to perfect heart valve sizing for tricky bicuspid patients

NCT ID NCT06991517

Recruiting now Disease control Sponsor: World Health Research Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study is testing a new CT-based sizing algorithm (the ABC Bicuspid Sizing Algorithm) to help doctors choose the right valve size and procedure for people with bicuspid aortic stenosis who need a transcatheter aortic valve replacement (TAVR). About 290 participants will have their CT scans analyzed using the algorithm to guide treatment. Researchers will check if this approach leads to better technical success right after the procedure and better valve function at 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ABC Bicuspid Sizing Algorithm (a CT scan evaluation tool)
What this could lead to: If successful, this algorithm could help doctors choose the right valve size and procedure for people with bicuspid aortic stenosis, potentially reducing complications and improving TAVR outcomes.
What could go wrong: This is an early-stage observational study, not a randomized trial. The algorithm may not improve outcomes for all patients, and results may not apply to everyone with this condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC STENOSIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Centro Médico Nacional Siglo XXI
RECRUITING

Mexico City, 06720, Mexico
Christchurch Hospital
RECRUITING

Christchurch, 4710, New Zealand
Fiona Stanley Hospital
RECRUITING

Murdoch, Western Australia, 6150, Australia
Foothills Medical Centre
RECRUITING

Calgary, Alberta, T2N 2T9, Canada
Fundación Cardioinfantil - LaCardio
RECRUITING

Bogotá, 111011, Colombia
Hamilton General Hospital
RECRUITING

Hamilton, Ontario, L8L 2X2, Canada
Hospital San Juan de Dios
NOT_YET_RECRUITING

San José, Provincia de San José, 10104, Costa Rica
Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
RECRUITING

Québec, Quebec, G1V 4G5, Canada
National Heart Centre Singapore
RECRUITING

Singapore, 169609, Singapore
North Shore Private Hospital
RECRUITING

St Leonards, New South Wales, 2065, Australia
NovaScotia Health Authority- Halifax Infimary
RECRUITING

Halifax, NovaScotia, B3H 3A7, Canada
Ramathibodi Hospital
NOT_YET_RECRUITING

Bangkok, 10400, Thailand
Royal North Shore Hospital
RECRUITING

St Leonards, New South Wales, 2065, Australia
Southlake Regional Health Centre
NOT_YET_RECRUITING

Newmarket, Ontario, L3Y 2P9, Canada
St Andrew's War Memorial Hospital
RECRUITING

Spring Hill, Queensland, 4000, Australia
St. Michael's Hospital
RECRUITING

Toronto, Ontario, M5B 1W8, Canada
The Alfred
RECRUITING

Melbourne, Victoria, 3004, Australia
The Prince Charles Hospital
RECRUITING

Chermside, Queensland, 4032, Australia
University of Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada
Wellington Regional Hospital
RECRUITING

Newtown, Wellington Region, 6021, New Zealand

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