New hope for Hard-to-Treat prostate cancer: first human trial launches

NCT ID NCT06318273

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug called ABBV-969 in men with a type of advanced prostate cancer that no longer responds to standard hormone therapy. The main goals are to check the drug's safety and find the best dose. About 230 participants worldwide will receive the drug through an IV, and the study will last up to 3 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AdventHealth Orlando /ID# 261686

    Orlando, Florida, 32803, United States

  • Ballarat Base Hospital /ID# 264294

    Ballarat, Victoria, 3350, Australia

  • Carolina BioOncology Institute /ID# 261602

    Huntersville, North Carolina, 28078, United States

  • Centre Hospitalier de l'Universite de Montreal (CHUM) /ID# 270890

    Montreal, Quebec, H2X 0C1, Canada

  • Centre Leon Berard /ID# 270605

    Lyon, Rhone, 69373, France

  • Centre Oscar Lambret /ID# 270602

    Lille, Nord, 59000, France

  • Chris O'Brien Lifehouse /ID# 261731

    Camperdown, New South Wales, 2050, Australia

  • City of Hope /ID# 262059

    Duarte, California, 91010, United States

  • Hadassah Medical Center-Hebrew University /ID# 261771

    Jerusalem, 91120, Israel

  • Hospital Universitario HM Sanchinarro /ID# 271345

    Madrid, 28050, Spain

  • Hospital Universitario Vall de Hebron /ID# 270889

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen del Rocio /ID# 270617

    Seville, 41013, Spain

  • Institut Gustave Roussy /ID# 270603

    Villejuif, Île-de-France Region, 94800, France

  • Kyoto University Hospital /ID# 261861

    Kyoto, Kyoto, 606-8507, Japan

  • Lifespan Cancer Institute at Rhode Island Hospital /ID# 261687

    Providence, Rhode Island, 02903-4923, United States

  • McGill University Health Centre - Glen Site. /ID# 271275

    Montreal, Quebec, H4A 3J1, Canada

  • NEXT Oncology /ID# 261601

    San Antonio, Texas, 78229, United States

  • National Cancer Center Hospital /ID# 261698

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East /ID# 261606

    Kashiwa-shi, Chiba, 277-8577, Japan

  • Rambam Health Care Campus- Haifa /ID# 261770

    Haifa, 3109601, Israel

  • START Midwest /ID# 264295

    Grand Rapids, Michigan, 49546, United States

  • St Vincent's Hospital /ID# 264293

    Fitzroy, Victoria, 3065, Australia

  • The Chaim Sheba Medical Center /ID# 261772

    Ramat Gan, Tel Aviv, 5265601, Israel

  • Univ California, San Francisco /ID# 261715

    San Francisco, California, 94143-2204, United States

  • University of Chicago Medical Center /ID# 261605

    Chicago, Illinois, 60637, United States

  • Yale University School of Medicine /ID# 262234

    New Haven, Connecticut, 06510, United States