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New pill shows promise in early trial for blood cancers

NCT ID NCT05618028

Ongoing Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This early-stage study tests a new drug called ABBV-525 in people with B-cell cancers like lymphoma and leukemia. The goal is to find a safe dose and see if it can shrink tumors. About 78 adults will take the drug by mouth at different doses over several months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center /ID# 266341

    Seoul, Seoul Teugbyeolsi, 05505, South Korea

  • Atrium Health Levine Cancer Institute /ID# 246363

    Charlotte, North Carolina, 28204, United States

  • Bankstown-Lidcombe Hospital /ID# 260191

    Bankstown, New South Wales, 2200, Australia

  • CHRU Lille - Hopital Claude Huriez /ID# 252054

    Lille, Nord, 59037, France

  • Charite Universitaetsmedizin Berlin Campus Virchow-Klinikum /ID# 252062

    Berlin, 13353, Germany

  • China Medical University Hospital /ID# 266414

    Taichung, 40447, Taiwan

  • Fort Wayne Medical Oncology and Hematology, Inc /ID# 250113

    Fort Wayne, Indiana, 46804, United States

  • Hadassah Medical Center-Hebrew University /ID# 251441

    Jerusalem, Jerusalem, 91120, Israel

  • Hospital Clinic de Barcelona /ID# 246543

    Barcelona, 08036, Spain

  • Hospital Universitario 12 de Octubre /ID# 246538

    Madrid, 28041, Spain

  • Hospital Universitario Ramon y Cajal /ID# 246540

    Madrid, 28034, Spain

  • Hospital Universitario Vall de Hebron /ID# 245475

    Barcelona, 08035, Spain

  • IUCT Oncopole /ID# 259409

    Toulouse, Occitanie, 31059, France

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center /ID# 259872

    Indianapolis, Indiana, 46202-5116, United States

  • Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 246537

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Leeds Teaching Hospitals NHS Trust /ID# 245470

    Leeds, West Yorkshire, LS9 7TF, United Kingdom

  • Memorial Sloan Kettering Cancer Center-Koch Center /ID# 245459

    New York, New York, 10065-6007, United States

  • Monash Health - Monash Medical Centre /ID# 246366

    Clayton, Victoria, 3168, Australia

  • Mount Sinai Medical Center-Miami Beach /ID# 248251

    Miami Beach, Florida, 33140-2948, United States

  • National Taiwan University Hospital /ID# 266343

    Taipei, 100, Taiwan

  • Northwest Medical Specialties - Tacoma /ID# 260376

    Tacoma, Washington, 98405, United States

  • Orange Health Service /ID# 260473

    Orange, New South Wales, 2800, Australia

  • Rabin Medical Center. /ID# 257665

    Petah Tikva, Central District, 4941492, Israel

  • START Midwest /ID# 252359

    Grand Rapids, Michigan, 49546, United States

  • Samsung Medical Center /ID# 266415

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Seoul National University Hospital /ID# 266340

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Shamir Medical Center /ID# 257711

    Beer Ya'akov, Central District, 70300, Israel

  • The Alfred Hospital /ID# 248592

    Melbourne, Victoria, 3004, Australia

  • The Chaim Sheba Medical Center /ID# 251442

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Christie Hospital /ID# 250325

    Manchester, M20 4BX, United Kingdom

  • The Royal Marsden NHS Foundation Trust /ID# 250324

    London, SW3 6JJ, United Kingdom

  • Tulane Cancer Center Clinic /ID# 249586

    New Orleans, Louisiana, 70112, United States

  • UZ Gent /ID# 246462

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • Universitair Ziekenhuis Leuven /ID# 246461

    Leuven, Vlaams-Brabant, 3000, Belgium

  • University Of Cincinnati Medical Center /ID# 262288

    Cincinnati, Ohio, 45219, United States

  • University of California Los Angeles Medical Center /ID# 246357

    Los Angeles, California, 90095, United States

  • University of Texas MD Anderson Cancer Center /ID# 245463

    Houston, Texas, 77030, United States

  • University of Utah Health Hospital /ID# 259924

    Salt Lake City, Utah, 84132, United States

  • Yale University School of Medicine /ID# 259081

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

B CELL MALIGNANCIES B-CELL MALIGNANCIES CHRONIC LYMPHOCYTIC LEUKEMIA DIFFUSE LARGE B CELL LYMPHOMA NON-HODGKIN'S LYMPHOMA