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New hope for tough cancers: first test of experimental drug begins

NCT ID NCT05029882

Ongoing Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This is the first study in people to test the safety and early effectiveness of an investigational drug called ABBV-400 for adults with advanced solid tumors that have stopped responding to standard treatments. The study will find the best dose of ABBV-400 given alone and will also test it in combination with another cancer drug, bevacizumab. It focuses on several hard-to-treat cancers, including non-small cell lung cancer, gastroesophageal cancer, and colorectal cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP-HP - Hopital Européen Georges Pompidou /ID# 250481

    Paris, 75015, France

  • Aichi Cancer Center Hospital /ID# 250284

    Nagoya, Aichi-ken, 464-8681, Japan

  • Asan Medical Center /ID# 245215

    Seoul, Seoul Teugbyeolsi, 05505, South Korea

  • Austin Health /ID# 247667

    Heidelberg, Victoria, 3084, Australia

  • CHA Bundang Medical Center /ID# 247115

    Seongnam, Gyeonggido, 13496, South Korea

  • CHU Nantes - Hopital Laennec /ID# 244723

    Saint-Herblain, Loire-Atlantique, 44800, France

  • Carolina BioOncology Institute /ID# 231541

    Huntersville, North Carolina, 28078, United States

  • Centre Antoine-Lacassagne /ID# 231730

    Nice, Provence-Alpes-Côte d'Azur Region, 06189, France

  • Centre Georges François Leclerc /ID# 244450

    Dijon, 21079, France

  • Centre Leon Berard /ID# 250987

    Lyon, Rhone, 69373, France

  • Changhua Christian Hospital /ID# 249150

    Changhua City, Changhua County, 50006, Taiwan

  • Chungbuk National University Hospital /ID# 245168

    Cheongju-si, North Chungcheong, 28644, South Korea

  • Clinica Universidad de Navarra - Pamplona /ID# 248816

    Pamplona, Navarre, 31008, Spain

  • Cmuh /Id# 245729

    Taichung, 40701, Taiwan

  • Community Health Network, Inc. /ID# 245331

    Indianapolis, Indiana, 46250-2042, United States

  • Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 245378

    Santiago de Compostela, A Coruna, 15706, Spain

  • Comprehensive Cancer Centers of Nevada /ID# 242930

    Henderson, Louisiana, 89052, United States

  • Duke Cancer Institute /ID# 247236

    Durham, North Carolina, 27710, United States

  • Duplicate_Gabrail Cancer Center Research /ID# 248419

    Canton, Ohio, 44718, United States

  • Duplicate_Kaohsiung Chang Gung Memorial Hospital /ID# 246449

    Kaohsiung City, Kaohsiung, 833, Taiwan

  • Fort Wayne Medical Oncology and Hematology - Fort Wayne - East Dupont Road /ID# 267338

    Fort Wayne, Indiana, 46825, United States

  • Gyeongsang National University Hospital /ID# 248420

    Jinju, Gyeongsangnam-do, 52727, South Korea

  • Hadassah Medical Center /ID# 243821

    Jerusalem, Jerusalem, 91120, Israel

  • Hospital Clinic de Barcelona /ID# 245374

    Barcelona, 08036, Spain

  • Hospital General Universitario Gregorio Maranon /ID# 245270

    Madrid, 28007, Spain

  • Hospital Universitario 12 de Octubre /ID# 248417

    Madrid, 28041, Spain

  • Hospital Universitario Fundacion Alcorcon /ID# 244505

    Alcorcón, Madrid, 28922, Spain

  • Hospital Universitario Fundacion Jimenez Diaz /ID# 231464

    Madrid, 28040, Spain

  • Hospital Universitario HM Sanchinarro /ID# 244721

    Madrid, 28050, Spain

  • Hospital Universitario Miguel Servet /ID# 244456

    Zaragoza, 50009, Spain

  • Hospital Universitario Vall de Hebron /ID# 249809

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen Macarena /ID# 245213

    Seville, 41009, Spain

  • Hospital Universitario de Jaen /ID# 249201

    Jaén, 23007, Spain

  • Indiana University Melvin and Bren Simon Cancer Center /ID# 245133

    Indianapolis, Indiana, 46202-5112, United States

  • Inje University Haeundae Hospital /ID# 244451

    Busan, Busan Gwang Yeogsi, 48108, South Korea

  • Institut Bergonie /ID# 248028

    Bordeaux, Gironde, 33000, France

  • Institut Gustave Roussy /ID# 246824

    Villejuif, Val-de-Marne, 94805, France

  • Institut de Cancérologie de l'Ouest René Gauducheau /ID# 248399

    Saint-Herblain, Loire-Atlantique, 44805, France

  • Instituto Catalan de Oncologia (ICO) Badalona /ID# 245379

    Badalona, Barcelona, 08916, Spain

  • Kangbuk Samsung Hospital /ID# 248401

    Seoul, Seoul Teugbyeolsi, 03181, South Korea

  • Koo Foundation Sun Yat-Sen Cancer Center /ID# 245917

    Taipei, 112, Taiwan

  • Korea University Guro Hospital /ID# 244504

    Seoul, Seoul Teugbyeolsi, 08308, South Korea

  • Kyoto University Hospital /ID# 250291

    Kyoto, Kyoto, 606-8507, Japan

  • Linkou Chang Gung Memorial Hospital /ID# 248716

    Taoyuan, 333, Taiwan

  • MD Anderson Cancer Center at Texas Medical Center /ID# 248656

    Houston, Texas, 77030-4000, United States

  • Mater Misericordiae Limited /ID# 249995

    South Brisbane, Queensland, 4101, Australia

  • Med Polonia Sp. z o. o. /ID# 250799

    Poznan, Greater Poland Voivodeship, 60-693, Poland

  • Meir Medical Center /ID# 244179

    Kfar Saba, Central District, 4428164, Israel

  • Memorial Sloan Kettering Cancer Center-Koch Center /ID# 250668

    New York, New York, 10065-6007, United States

  • NEXT Oncology /ID# 231578

    San Antonio, Texas, 78229, United States

  • NHO Nagoya Medical Center /ID# 250286

    Nagoya, Aichi-ken, 460-0001, Japan

  • Nagasaki University Hospital /ID# 250290

    Nagasaki, 852-8501, Japan

  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Bada /ID# 246569

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • National Cancer Center Hospital /ID# 232007

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East /ID# 232008

    Kashiwa-shi, Chiba, 277-8577, Japan

  • National Cheng Kung University Hospital /ID# 245918

    Tainan, 704, Taiwan

  • National Taiwan University Hospital /ID# 245731

    Taipei City, Taipei, 100, Taiwan

  • Niigata University Medical & Dental Hospital /ID# 250952

    Niigata, Niigata, 951-8520, Japan

  • Northwest Medical Specialties Tacoma /ID# 267339

    Tacoma, Washington, 98405, United States

  • Oncology Consultants /ID# 267347

    Houston, Texas, 77030, United States

  • Pan American Center for Oncology Trials, LLC /ID# 231580

    Rio Piedras, 00935, Puerto Rico

  • Rabin Medical Center /ID# 243363

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus /ID# 231218

    Haifa, 3109601, Israel

  • SMG-SNU Boramae Medical Center /ID# 248421

    Seoul, Seoul Teugbyeolsi, 07061, South Korea

  • START Midwest /ID# 231551

    Grand Rapids, Michigan, 49546-7062, United States

  • Samodzielny Publiczny Zespó? Gru?licy i Chorób P?uc w Olsztynie /ID# 250466

    Olsztyn, 10-357, Poland

  • Seoul National University Hospital /ID# 244667

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Taipei Medical University Hospital /ID# 245732

    Taipei, 11031, Taiwan

  • Taipei Veterans General Hosp /ID# 250652

    Taipei, 11217, Taiwan

  • Tel Aviv Sourasky Medical Center /ID# 245271

    Tel Aviv, Tel Aviv, 6423906, Israel

  • The Cancer Institute Hospital Of JFCR /ID# 248447

    Koto-ku, Tokyo, 135-8550, Japan

  • The Chaim Sheba Medical Center /ID# 231217

    Ramat Gan, Tel Aviv, 5265601, Israel

  • Tri-Service General Hospital /ID# 245733

    Taipei, 114, Taiwan

  • University Of Colorado Denver /ID# 231574

    Aurora, Colorado, 80045-2530, United States

  • University of California, Los Angeles /ID# 243841

    Los Angeles, California, 90095, United States

  • University of Illinois Hospital and Health Sciences System /ID# 251386

    Chicago, Illinois, 60607, United States

  • Virginia Cancer Specialists - Fairfax /ID# 231575

    Fairfax, Virginia, 22031, United States

  • Wakayama Medical University Hospital /ID# 250283

    Wakayama, Wakayama, 641-8510, Japan

  • Wojewodzki Szpital im. Sw. Ojca Pio /ID# 251846

    Przemyśl, Podkarpackie Voivodeship, 37-700, Poland

  • Yale School of Medicine /ID# 248418

    New Haven, Connecticut, 06519, United States

  • Yokohama Municipal Citizen's Hospital /ID# 248842

    Yokohama, Kanagawa, 221-0855, Japan

  • Yonsei University Health System Severance Hospital /ID# 245218

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.

ADVANCED SOLID TUMORS COLORECTAL CANCER GASTROESOPHAGEAL ADENOCARCINOMA NON SMALL CELL LUNG CANCER