New radioactive therapy targets tough childhood cancer

NCT ID NCT04023331

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a radioactive drug called 67Cu-SARTATE in 21 children with high-risk neuroblastoma that had relapsed or not responded to treatment. The drug is designed to deliver radiation directly to tumor cells. The goal was to find the safest dose and see if it shrinks tumors. The trial was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

67Cu-SARTATE (a radioactive drug that targets tumor cells)

What this could lead to

If successful, this could provide a new treatment option for children with hard-to-treat neuroblastoma that has come back or not responded to standard therapy.

What could go wrong

This is an early-phase trial with only 21 participants, so results may not apply broadly. The trial was terminated, which may indicate challenges. Radiation therapy can cause side effects like low blood counts or organ damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Centre

    Cincinnati, Ohio, 45229, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • University of Texas Southwestern Medical Centre

    Dallas, Texas, 75390, United States

  • University of Wisconsin

    Madison, Wisconsin, 53792, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States