Cure My Disease

Don't miss your cure!

 Log in / Sign up

Five days of radiation instead of weeks: a new test for head and neck cancer

NCT ID NCT05648461

Disease control Sponsor: All India Institute of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers are testing a shorter radiation schedule for people with head and neck cancer who have had surgery. Standard radiation after surgery often takes several weeks, but this trial gives five treatments over five days. The study enrolls 50 adults with high-risk features, such as close surgical margins or lymph node involvement. Doctors track whether the shorter course controls the cancer and whether it causes severe long-term side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a shorter course of radiation therapy after surgery
What this could lead to
If it works, this could offer a faster, more convenient radiation schedule for people with head and neck cancer after surgery.
What could go wrong
The trial is small and early. The shorter schedule may not control cancer as well as standard treatment, or it may cause unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Expected to start

Mar 2023

An estimate. Start dates often move.

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged 18 or above and less than 80 years. 2. Patient with high risk features: close (≤ 5mm) margin, presence of LVI or PNI, pT3-4. 3. Stage pT1-4 histological confirmed carcinoma of oral cavity with intermediate high risk feature. 4. Pathological N0 neck requiring ipsilateral neck PORT. 5. Karnofsky performance score greater or equal 70. 6. Timely delivery of PORT preferable within 6-12 weeks of surgery (additional delay of 1-3 weeks of delay beyond 12 weeks is permissible to accommodate for delayed wound healing or other logistics). 7. Written informed consent for treatment. 8. Available to attend long term follow- up. Exclusion Criteria: 1. Pathologically positive neck disease. 2. Positive margin. 3. Patients requiring bilateral neck RT. 4. Patients that require re-irradiation for recurrent disease. 5. Previous radiotherapy to the head and neck region. 6. Any invasive malignancy within the previous 2 years (other than non melanomatous skin carcinoma or cervical carcinoma in situ). 7. Age \< 18 years or \> 80 years.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Head and neck cancer are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms oral cavity carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Head and neck cancer

Contacts and locations

Locations

  • Nci, Aiims-Jhajjar

    Jhajjar, Haryana, 124105, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.