New gallbladder drug trial: does food change how it works?
NCT ID NCT07594977
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study is testing a new tablet called 4-MUST in 45 healthy volunteers. Researchers want to see if taking the drug with food changes how much gets into the blood, and how safe and tolerable it is after single and repeated doses. The results will help design future studies for people with chronic cholecystitis (gallbladder inflammation) and biliary dyskinesia (bile duct movement problems).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 4-MUST (trimebutine 4-methylumbelliferyl sulfate) tablets
- What this could lead to
- If successful, this study could help determine the best way to take 4-MUST (with or without food) for future trials in people with gallbladder or bile duct issues.
- What could go wrong
- This is a very early Phase 1 trial in only 45 healthy volunteers, not patients. It focuses on drug levels and safety, not on treating any disease. The results may not predict how the drug works in people who are actually sick.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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I.M. Sechenov First Moscow State Medical University
RECRUITINGMoscow, 119991, Russia
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Other studies related to the condition(s) this trial covers.