Could a new tracer revolutionize Alzheimer's diagnosis?

NCT ID NCT07306598

First seen Jan 08, 2026 · Last updated Jun 20, 2026 · Updated 26 times

Summary

This study tests a new radioactive tracer called [18F]NIDF for PET scans. The tracer is designed to bind to tau tangles in the brain, which are linked to Alzheimer's and other neurodegenerative diseases. Researchers want to see if it is safe and can produce clearer images than current tracers. The study involves 20 healthy volunteers and patients with Alzheimer's or related conditions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of University of Science and Technology of China

    RECRUITING

    Hefei, Anhui, 230000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 350005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]NIDF (a radioactive tracer for PET imaging)

What this could lead to

If successful, this could lead to a more accurate way to diagnose Alzheimer's and other tau-related brain diseases using PET scans.

What could go wrong

This is a very early, small study (20 people) focused on safety and imaging quality. The tracer may not prove better than existing methods, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

Alzheimer disease neurodegenerative disease tauopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.