New PET scan agent could spot childhood cancer more clearly

NCT ID NCT04724369

Ongoing Diagnosis Sponsor: Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This Phase 3 trial tests a radioactive imaging agent called 18F-mFBG to see if it can accurately detect neuroblastoma, a type of childhood cancer. The study involves 43 participants who either have or are suspected of having neuroblastoma. Researchers will compare the new PET scan method with standard imaging to see if it improves diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 18F-mFBG (a radioactive imaging agent)
What this could lead to: If successful, this could provide a more accurate and faster way to detect neuroblastoma, helping doctors make better treatment decisions.
What could go wrong: This is a small Phase 3 trial with only 43 participants, so results may not apply to all patients. The imaging agent may not be significantly better than existing methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROBLASTOMA

Contacts and locations

Locations

Children's Hospital Los Angeles

Los Angeles, California, 90027, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Riley Hospital for Children - Indiana University

Indianapolis, Indiana, 46202, United States
The Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
University of California, San Francisco

San Francisco, California, 94143, United States
University of Michigan Health System

Ann Arbor, Michigan, 48109, United States

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