New scan spots tiny pancreatic tumors that cause dangerous low blood sugar

NCT ID NCT01916148

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study offers expanded access to a PET scan using a radioactive tracer called 18F-DOPA to locate small, insulin-producing lesions in the pancreas. It is for patients with congenital hyperinsulinism, Beckwith-Wiedemann syndrome, or insulinoma who have low blood sugar. The goal is to pinpoint the lesion's location to guide surgical removal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-DOPA (a radioactive tracer used in PET scans)

What this could lead to

If successful, this imaging technique could help doctors precisely locate insulin-producing lesions in the pancreas, guiding surgery and potentially curing hypoglycemia.

What could go wrong

This is an expanded access program, not a formal trial, so evidence is limited. The scan may not detect all lesions, and results depend on individual patient factors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Beckwith-Wiedemann syndrome Congenital Hyperinsulinism familial hyperinsulinism hyperinsulinism hypoglycemia pancreatic insulinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    AVAILABLE

    Philadelphia, Pennsylvania, 19104, United States

    Contact