2000-Patient study aims to uncover hidden metabolic risks in rare genetic disorders
NCT ID NCT05945576
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study will follow 2000 children and adults with imprinting disorders—rare genetic conditions like Silver-Russell and Prader-Willi syndromes. Researchers aim to describe the natural history of these diseases and identify common metabolic profiles, risks for obesity, diabetes, and heart disease. No treatment is being tested; the goal is to improve understanding and future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better predict and manage metabolic complications like obesity and diabetes in people with imprinting disorders.
- What could go wrong
- This is an observational study, not a treatment trial. It will not test any new therapy, and results may take years to influence clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU d'Angers
NOT_YET_RECRUITINGAngers, France
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Hôpital Armand-Trousseau
RECRUITINGParis, France
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Hôpital Bicêtre
RECRUITINGLe Kremlin-Bicêtre, France
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Hôpital Brabois
NOT_YET_RECRUITINGNancy, France
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Hôpital Bretonneau
NOT_YET_RECRUITINGTours, France
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Hôpital Civil
NOT_YET_RECRUITINGStrasbourg, France
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Hôpital Femme Mère Enfant
NOT_YET_RECRUITINGLyon, France
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Hôpital Gabriel Montpied
NOT_YET_RECRUITINGClermont-Ferrand, France
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Hôpital Jean Minjoz
NOT_YET_RECRUITINGBesançon, France
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Hôpital Jeanne de Flandre
NOT_YET_RECRUITINGLille, France
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Hôpital Necker Enfants Malades
RECRUITINGParis, France
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Hôpital Robert Debré
NOT_YET_RECRUITINGParis, France
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Hôpital Sud
RECRUITINGRennes, France
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Hôpital de la Pitié-Salpêtrière
RECRUITINGParis, France
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Hôpital de la Pitié-Salpêtrière
RECRUITINGParis, France
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Hôpital de la Timone
RECRUITINGMarseille, France
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Hôpital de la mère et de l'enfant
NOT_YET_RECRUITINGLimoges, France
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Hôpital des Enfants
RECRUITINGToulouse, France
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Hôpital des Enfants
NOT_YET_RECRUITINGToulouse, France
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Hôpital enfant-adolescent
NOT_YET_RECRUITINGNantes, France
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