Wright State University
Clinical trials sponsored by Wright State University, explained in plain language.
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Can a common antidepressant cream stop Burn-Induced cellular 'Debris'?
Knowledge-focused Not yet recruitingThis study investigates whether a topical cream containing amitriptyline, a drug typically used for depression and pain, can block the release of microvesicle particles (MVPs) from skin after a small thermal burn. Healthy adults aged 18-64 receive a tiny, controlled burn on their…
Phase: PHASE1 • Sponsor: Wright State University • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Can a common antidepressant calm burn damage? early study investigates
Knowledge-focused Not yet recruitingThis pilot study tests whether a single 75mg dose of amitriptyline can reduce the release of microvesicle particles (tiny substances) from skin after a very small, controlled burn. Twenty healthy adults will receive either amitriptyline or a placebo, then a small heated rod creat…
Phase: PHASE1 • Sponsor: Wright State University • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC