Magic mushroom compound shows promise for depression in large trial
Symptom relief
Completed
This study tested whether a single 25 mg dose of psilocybin, the active ingredient in magic mushrooms, could reduce depression symptoms better than a placebo (niacin). 347 adults with major depressive disorder received either psilocybin or niacin in a double-blind setup. The main…
Phase: PHASE2 • Sponsor: Usona Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC