University Of Nottingham

This study looks at how changing physical activity levels impacts the body in adults aged 50-65 who are overweight. Some participants will reduce their activity for 3 months, then retrain, while others will increase activity for 6 months. Researchers will measure fitness, muscle …

This study uses MRI scans to see exactly where the drug linaclotide works in the gut. Linaclotide is currently used for constipation, but researchers want to know if it could help people with cystic fibrosis, who have trouble moving fluid through their intestines. 26 healthy adul…

This study observes 160 cancer patients to understand why some develop liver injury from checkpoint inhibitor drugs. Researchers will track blood markers and genetic factors to identify who is at risk. No new treatment is tested; the goal is to improve diagnosis and monitoring.

This study looks at how to improve follow-up care for people who have had acute kidney injury (AKI). Researchers will compare two blood tests (creatinine and cystatin) to see which better measures kidney function after AKI. They will also interview patients about their experience…

This study explores whether a simple, non-invasive technique called Remote Ischaemic Conditioning (RIC) can improve how the brain regulates its own blood flow in healthy older adults. RIC involves briefly restricting blood flow to one arm using a cuff, then releasing it. The tria…

This study looks at whether adjusting the difficulty of online listening exercises can help adults with hearing problems learn better. Researchers will have 120 participants do 30 minutes of training per day for two weeks. The goal is to understand how task difficulty affects lis…