University Hospital Southampton Nhs Foundation Trust

This early-phase study tests a new combination of three drugs (radioactive therapy, an immunotherapy, and a checkpoint inhibitor) in children whose neuroblastoma has come back or not responded to treatment. The main goal is to see if the combination is safe and tolerable. About 4…

This study looks at whether adding the drug acalabrutinib to standard chemotherapy (R-CHOP) helps people with a type of blood cancer called diffuse large B-cell lymphoma (DLBCL). About 450 adults with untreated DLBCL will receive one round of standard chemo, then two-thirds will …

This study looks at a new way to analyze brain scans, called Cortical Disarray Measurement (CDM), to see if it can help diagnose Alzheimer's disease more accurately. Researchers will follow 400 people with mild memory or thinking problems over time. The goal is to see if CDM chan…