University Hospital, Essen
Clinical trials sponsored by University Hospital, Essen, explained in plain language.
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Immunotherapy before lung surgery shows promise in early trial
Disease control CompletedThis study tested giving immunotherapy drugs (nivolumab alone or with relatlimab) for four weeks before surgery in 90 people with early-stage non-small cell lung cancer. The goal was to see if this approach is feasible and helps shrink tumors before removal. Results help determin…
Phase: PHASE2 • Sponsor: University Hospital, Essen • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Triple-Drug cocktail shows promise for tough bile duct cancer
Disease control CompletedThis study tested a combination of three drugs—chemotherapy (mFOLFOX6), an immunotherapy (atezolizumab), and a targeted therapy (bevacizumab)—in 20 people with advanced bile duct cancer who had already received one prior treatment. The goal was to see if the combination could shr…
Phase: PHASE1, PHASE2 • Sponsor: University Hospital, Essen • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Brain bleed breakthrough? new study tests antidote for blood thinner patients
Knowledge-focused CompletedThis study observed 141 people in German stroke units who had a brain bleed while taking the blood thinners rivaroxaban or apixaban. Researchers wanted to see if giving the reversal drug andexanet alfa could stop the bleed from getting bigger. They tracked changes in bleed size o…
Sponsor: University Hospital, Essen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Heart study reveals best ways to measure hidden pressure
Knowledge-focused CompletedThis study looked at 623 adults with heart failure or high blood pressure in the lungs to see how well different tests measure pressure inside the heart. Doctors used both non-invasive ultrasound (echocardiogram) and invasive catheter measurements to check for elevated filling pr…
Sponsor: University Hospital, Essen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC