Therapeutic Advances In Childhood Leukemia Consortium

This study tested a new way to treat children and young adults (ages 1 to 25) with acute myeloid leukemia (AML) that has come back or is hard to treat. The approach uses two drugs (decitabine and vorinostat) to 'reprogram' leukemia cells before giving standard chemotherapy (FLAG)…

This study tested a new form of the chemotherapy drug vincristine (called Marqibo) combined with standard relapse treatment for children, teens, and young adults with acute lymphoblastic leukemia (ALL) that had come back. The main goal was to find a safe dose and see how well the…