Therapeutic Advances In Childhood Leukemia Consortium

This study tested whether adding two drugs (decitabine and vorinostat) before standard chemotherapy could help children and young adults whose acute myeloid leukemia (AML) has come back or hasn't responded to treatment. The main goal was to find the safest dose of this new combin…

This study tested the safety of a modified chemotherapy regimen for children and young adults whose acute lymphoblastic leukemia (ALL) had returned. It replaced one standard drug with a special, longer-acting version (Marqibo®) within a known treatment combination. The main goal …