Therapeutic Advances In Childhood Leukemia Consortium
Clinical trials sponsored by Therapeutic Advances In Childhood Leukemia Consortium, explained in plain language.
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Experimental liposomal chemo shows promise in kids with relapsed leukemia
Disease control CompletedThis pilot study tested a liposomal form of the chemotherapy drug vincristine (Marqibo) combined with standard UK ALL R3 chemotherapy in 29 children, adolescents, and young adults with relapsed acute lymphoblastic leukemia. The main goal was to see if it was safe and tolerable at…
Phase: PHASE1 • Sponsor: Therapeutic Advances in Childhood Leukemia Consortium • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New hope for young AML patients: epigenetic drugs plus chemotherapy show promise
Disease control CompletedThis early-phase study tested whether adding two drugs (decitabine and vorinostat) before and during standard chemotherapy (FLAG) is safe for children and young adults up to age 25 with acute myeloid leukemia (AML) that has come back or not responded to treatment. The goal was to…
Phase: PHASE1 • Sponsor: Therapeutic Advances in Childhood Leukemia Consortium • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC