The University Of Texas Health Science Center, Houston

This study is testing whether reducing the amount of intravenous (IV) fat given to extremely premature babies can help protect their brains from bilirubin, a substance that can cause damage. Researchers are comparing the usual amount of IV fat to a reduced amount in 134 infants, …

This study is testing whether deep brain stimulation (DBS), a surgical treatment sometimes called a 'brain pacemaker,' can help people with severe depression that hasn't improved with other treatments like multiple medications, therapy, or electroconvulsive therapy (ECT). Researc…

This study is testing a telehealth program to help people control their blood pressure after a stroke. The program includes video check-ups with a care team and home blood pressure monitoring. Researchers want to see if this approach improves health and reduces racial disparities…

This study aimed to test how well a device called RetroPerc® works during surgery to remove large kidney stones. It planned to measure things like surgery time, hospital stay, and whether patients became stone-free. The trial was withdrawn by the sponsor before any patients were …

This study tests whether a comprehensive program of lifestyle changes, medication, and special heart scans (PET imaging) works better than standard medical care alone for people with or at high risk for heart disease. Over 1,000 participants were randomly assigned to one of the t…

This study is testing whether a home compression pump can improve the body's natural fluid drainage system in people with leg swelling caused by vein problems. Researchers will compare 34 participants who use the pump daily for about a month against a group receiving standard car…

This study aims to find the best approach for treating hidden hernias that can't be felt during a physical exam. Researchers are comparing immediate surgery against watchful waiting in 252 patients to see which leads to better outcomes and fewer complications. The goal is to crea…

This study is testing whether an extremely intensive upper arm therapy program is practical and helpful for people living with long-term effects of a stroke. It involves six hours of daily therapy to try to improve arm movement, reduce disability, and boost quality of life. The r…

This study is testing a new program to help community health centers provide better long-term care for people who have survived cancer. It involves over 5,500 patients and their care teams. The goal is to improve screening for new cancers and make sure survivors get the recommend…

This study aimed to compare two different heart ablation techniques for people with a type of irregular heartbeat called atrial fibrillation. It planned to test if a newer, more targeted ablation method using advanced mapping technology was faster, safer, or more effective than t…

This study is testing a new material—a patch made from donated umbilical cord tissue—to repair spina bifida in unborn babies. The goal is to create a watertight seal over the spinal cord defect during a special prenatal surgery. Researchers hope this will lower the risk of seriou…

This program aims to help people with opioid addiction by quickly connecting them to treatment after an overdose or emergency room visit. It combines medication, counseling, peer support, and follow-up care. The goal is to see if this coordinated approach helps people start and s…

This study is testing whether giving very premature infants a higher daily dose of vitamin D (800 IU) during their first 28 days improves their health outcomes. Researchers will compare this to usual care in 180 babies born before 28 weeks or weighing less than 2.2 pounds. They w…

This study is testing whether a culturally tailored lifestyle program called Healthy Liver/Hígado Sano can help Hispanic adults with fatty liver disease lose weight and improve their liver health. Researchers will compare participants in the program to those receiving usual care …

This study aimed to see if a small, temporary ultrasound probe placed down the throat could help doctors make better treatment decisions for critically ill patients. It planned to observe 60 patients in trauma and heart surgery recovery, comparing this new monitoring method to st…

This study is testing whether starting a simple home therapy early can prevent painful facial and neck swelling (lymphedema) in people who have been treated for head and neck cancer. Researchers will use a special imaging scan to spot early signs of swelling and then have one gro…

This study aimed to see if allowing patients to drink clear liquids up to one hour before surgery is as safe as the traditional rule of no food or drink after midnight. Researchers wanted to compare patient comfort, nausea, and pain, as well as how it affects operating room sched…

This study is testing an online group program designed to help people who have lived with spinal cord injuries for many years. The program aims to improve physical health, reduce pain, and enhance mental wellbeing and social connection. Researchers are comparing the online progra…

This study is testing a non-invasive therapy called auricular point acupressure to see if it can ease the pain, numbness, and tingling caused by chemotherapy. Researchers are enrolling 225 adult cancer survivors who have these symptoms. Participants will tape small seeds to speci…

This study is testing whether a new at-home video rehabilitation program, supported by community health workers, is a practical way to help people recover after a stroke. It involves 11 stroke survivors in the Rio Grande Valley of Texas. The main goal is to see if this home-based…

This study aims to better understand the biology of different headache disorders, including migraines and cluster headaches. Researchers will use capsaicin (from chili peppers) and ice water to trigger mild, temporary pain responses in participants with headaches and healthy volu…

This study aimed to understand how a gentle, non-invasive ultrasound technique affects brain activity related to emotions and thinking in healthy volunteers. Researchers planned to use brain scans to see if the ultrasound could safely change activity in areas linked to mood. The …

This study aims to understand how the brain learns and remembers fear and avoidance behaviors. Researchers will measure brain activity and skin sweat responses in 150 healthy participants as they view images and learn to avoid mild shocks. The goal is to map the brain circuits in…

This research follows over 1,500 people for more than a decade to identify what factors increase or decrease the risk of gun access and use in dating relationships. The study combines surveys, interviews, and official records to understand why some people carry or use firearms in…