The University Of Texas Health Science Center, Houston

This study looks at whether giving a higher dose of vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) can improve their health. Researchers will check vitamin D levels and measure effects on the lungs, bones, immune system…

This study looks at whether giving extra vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) improves their lung, bone, immune, and brain health. About 180 babies will receive either the extra vitamin D or usual care for the…

This study tracks 100 people with pancreatic cysts or tumors who receive a treatment called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA). A thin needle delivers heat directly to the lesion to destroy it. Researchers will monitor how well the procedure works and …

This study planned to test a device called RetroPerc that helps doctors reach and remove large kidney stones. It was designed for adults with kidney stones larger than 10 mm. However, the study was withdrawn before any participants were enrolled, so no results are available.

This study tests whether a comprehensive program of lifestyle changes (diet, exercise, education) plus aggressive cholesterol-lowering drugs, guided by PET heart scans, can reduce heart attacks and deaths better than standard medical care. Over 1,000 adults with suspected or know…

This study tests a lifestyle program called Healthy Liver/Hígado Sano for Hispanic patients with metabolic-dysfunction associated steatotic liver disease (MASLD), also known as fatty liver disease. The program includes education sessions and family support to help participants lo…

This study tests whether deep brain stimulation (DBS) can help people with severe depression that hasn't improved with other treatments. Sixteen adults aged 22 to 70 will have electrodes implanted in a brain region called the medial forebrain bundle. The device delivers mild elec…

This pilot study was designed to test a new, more targeted way to perform ablation for atrial fibrillation (AFib). Instead of burning a wide area around the pulmonary veins, doctors would use special mapping technology to precisely target the heart muscle sleeves causing the abno…

This study tests whether giving extremely preterm babies less intravenous (IV) fat (lipids) can lower harmful bilirubin levels and protect their brain development. Bilirubin can build up in these tiny infants and cause hearing loss or long-term disabilities. Researchers will comp…

This study tests a program called HEROES that combines medication (Suboxone), counseling, and community outreach to help people with opioid use disorder engage and stay in treatment. Researchers will enroll 3,000 participants in Houston to see if this approach improves treatment …

This study tests whether a video-based telehealth program, including an iPad and remote blood pressure monitoring, can help stroke survivors better control their blood pressure after leaving the hospital. The program also aims to reduce racial disparities in post-stroke care. Abo…

This study tests a new way to repair spina bifida before birth using a tiny camera and a patch made from donated human umbilical cord tissue. The patch is placed over the spinal cord to create a watertight seal, which may reduce problems after birth. The trial includes 50 pregnan…

This study uses a special camera and a safe dye to take pictures of the lymphatic system, which helps move fluid in the body. Researchers want to see how this system works in healthy people and in those with conditions like lymphedema or lipedema. The goal is to find patterns tha…

This study tests whether starting physiotherapy early—before any swelling appears—can prevent lymphedema in people treated for head and neck cancer. Twenty participants will either use a home compression device daily or receive standard care. Researchers will track swelling and u…

This study tests whether a mobile app, supported by a community health worker, can help stroke survivors recover at home. Eleven uninsured stroke survivors in Texas will use the app for personalized exercises and receive support. The goal is to see if this approach improves mobil…

This study tests whether pressing specific points on the ear (auricular point acupressure) can reduce pain, numbness, and tingling caused by chemotherapy. About 225 cancer patients will try this non-needle technique. Researchers will also measure changes in nerve function and bod…

This study tests whether a high-dose, intensive therapy program can improve arm movement and quality of life in people who had a stroke at least 6 months ago. Nine participants will receive 6 hours of therapy per day, 5 days a week, for 3 weeks, including occupational and physica…

This large observational study aims to collect medical data and biological samples from up to 5,000 people with chronic spinal cord injury or traumatic brain injury, as well as their family members and healthy volunteers. Researchers hope this information will help them better un…

This study tests a program that offers housing and on-site employment to adults who are at risk of homelessness. Researchers want to see if this approach reduces emergency room visits and improves housing stability, employment, and quality of life. About 750 participants will be …

This study aimed to see if giving antibiotics to pregnant people whose water broke very early (before 22 weeks) could delay delivery and improve baby health. It was planned for those with a single baby and recent membrane rupture. However, the study was withdrawn before enrolling…

This study tests an 8-week online group program called Living Longer and Stronger with SCI, designed to help people with spinal cord injury improve their physical, mental, and social health as they age. Participants set health goals and make weekly action plans with support from …

This study looks at how headaches work by using capsaicin (the spicy part of chili peppers) and ice water to trigger mild, temporary pain in people with and without headache disorders. Researchers measure changes in pain signals and tear production to better understand conditions…

This study looks at what to do when a surgeon finds a small, hidden groin hernia during a routine hernia repair. It compares fixing it right away versus just watching it over time. The goal is to help patients and doctors decide the best approach by creating a simple decision-mak…

This study was designed to see if low-intensity focused ultrasound could safely change brain activity related to emotion and thinking. It planned to test the device on healthy volunteers using brain scans. However, the study was withdrawn before enrolling any participants, so no …

This study follows 1,500 teens and young adults over time to understand what factors increase or decrease the risk of gun access, carrying, and use in the context of dating violence. Researchers will also interview known gun carriers to learn about their experiences. The goal is …

This study looks at how the brain learns to be afraid and how it learns to avoid things. About 150 healthy adults will look at pictures on a screen and sometimes get a mild shock. By measuring brain waves and sweat, researchers hope to understand the brain circuits involved in fe…

This study tests a program to help community health clinics provide better follow-up care for cancer survivors. The program includes training for clinic staff, tracking of patients' cancer history, and coordinating care. Researchers will study whether this approach improves scree…

This study planned to observe how a special, continuous-use ultrasound probe placed in the esophagus helps doctors make treatment decisions for patients with unstable blood pressure. It aimed to enroll 60 adults from trauma and heart surgery units. However, the study was withdraw…

This study aimed to see if having clear liquids up to one hour before gallbladder surgery is as safe as the standard overnight fast. It planned to measure stomach contents, patient comfort, and surgery scheduling. However, the study was withdrawn before enrolling any participants…

This study looks at whether a pneumatic compression device can improve lymphatic function in people with leg swelling from chronic venous disease. 34 participants will be split into two groups: one gets standard compression bandages, the other adds daily pneumatic compression at …