St. Joseph's Hospital And Medical Center, Phoenix

This study is testing whether siponimod, an oral medication already approved for multiple sclerosis, can slow brain shrinkage in people with mild Alzheimer's disease. Over 18 months, 105 participants will take either siponimod or a placebo pill to see if the drug is safe and if i…

This early-stage study is testing an experimental drug called BDTX-1535 in people with aggressive brain tumors (high-grade glioma or glioblastoma) that have specific genetic changes in a protein called EGFR. The research aims to see if the drug reaches brain tumor tissue effectiv…

This study aims to understand how ALS develops by closely monitoring 600 adults who have a family history of the disease but don't yet show symptoms. Participants will be followed for 3 years with regular check-ins, blood tests, and symptom tracking to identify early warning sign…

This study aims to collect detailed information from 2000 people, including those with ALS and healthy volunteers, over two years. Researchers will track symptoms, collect blood samples, and gather voice recordings to create a large database for scientists. The goal is to better …