Springworks Therapeutics, Inc., A Healthcare Company Of Merck Kgaa, Darmstadt, Germany

This study looked at how a common seizure medicine, carbamazepine, changes the amount of mirdametinib in the blood. 36 healthy adults took both drugs by mouth. The goal was to understand how the body processes mirdametinib when taken with carbamazepine, which can help doctors dec…

This study looked at how two common heartburn medications, famotidine and rabeprazole, affect the levels of nirogacestat in the blood of 24 healthy men. Participants took nirogacestat alone and with each heartburn drug to see if the combination changes how much medicine gets into…

This study looks at whether the drug nirogacestat affects how the body breaks down other common medications. Twenty healthy men will take nirogacestat along with a mix of five other drugs to measure any changes. The goal is to understand safety and dosing, not to treat any diseas…