Replimune, Inc.

This study tests an experimental drug called RP1, which is injected directly into skin tumors, for people who have had an organ or stem cell transplant and now have advanced skin cancer. The goal is to see if RP1 can shrink or control the cancer while being safe for the transplan…

This program offers early access to an experimental treatment (VO) combined with the standard drug nivolumab for adults with advanced melanoma that has worsened after prior anti-PD-1 therapy. The goal is to provide potential benefit to eligible patients before the drug is fully a…

This study tests an experimental drug called RP1, given alone or with the immunotherapy nivolumab, in people with advanced solid tumors like melanoma, lung cancer, and certain skin cancers. The goal is to see if the combination can shrink tumors and control the disease, but it is…

This early-stage study is testing a modified virus called RP3, both alone and combined with an existing immunotherapy drug, in people with advanced solid tumors that haven't responded to standard treatments. The main goals are to find the safest dose and understand the side effec…