Principia Biopharma, A Sanofi Company
Clinical trials sponsored by Principia Biopharma, A Sanofi Company, explained in plain language.
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New pill shows promise for hard-to-treat blood disorder
Disease control CompletedThis study tested an experimental oral drug called PRN1008 in 86 adults with immune thrombocytopenia (ITP) whose disease had returned or did not respond to other treatments. The goal was to see if the drug could safely raise platelet counts to safer levels and reduce bleeding ris…
Phase: PHASE2 • Sponsor: Principia Biopharma, a Sanofi Company • Aim: Disease control
Last updated May 17, 2026 04:47 UTC
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New drug combo shows promise for rare autoimmune disease
Disease control CompletedThis study tested a new drug called rilzabrutinib, given with steroids, to see if it can better control IgG4-related disease (a rare condition where the immune system attacks the body). 27 adults with active disease took part. The goal was to see if the drug combination could pre…
Phase: PHASE2 • Sponsor: Principia Biopharma, a Sanofi Company • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New eczema cream shows promise in early trial
Symptom relief CompletedThis study tested a new cream called PRN473 on 39 adults with mild to moderate eczema. Each person had two patches of eczema treated: one with the study cream and one with a placebo (fake cream) to compare. The main goal was to check safety and how the body processes the cream. T…
Phase: PHASE2 • Sponsor: Principia Biopharma, a Sanofi Company • Aim: Symptom relief
Last updated May 17, 2026 04:45 UTC
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Healthy volunteers test how breakfast changes drug absorption
Knowledge-focused CompletedThis study looked at how taking a drug called rilzabrutinib with or without food, and in different pill forms, changes its levels in the blood. 24 healthy adults each took a single dose under different conditions. The goal was to gather information for future dosing, not to treat…
Phase: PHASE1 • Sponsor: Principia Biopharma, a Sanofi Company • Aim: Knowledge-focused
Last updated May 17, 2026 04:44 UTC