Principia Biopharma, A Sanofi Company

This study tested whether adding a new oral drug called rilzabrutinib to standard steroid treatment could better control disease activity in adults with IgG4-related disease, a rare condition where the immune system attacks the body's own tissues. About 27 participants were split…

This study tested a new topical cream called PRN473 for adults with mild to moderate eczema. In 39 participants, researchers applied the cream to one skin patch and a placebo cream to another to compare safety and early signs of effectiveness. The main goal was to see if the trea…

This study tested a new oral medication called PRN1008 (rilzabrutinib) for adults with immune thrombocytopenia (ITP), a condition causing dangerously low platelet counts. It involved about 86 people whose previous treatments had stopped working or didn't help enough. The main goa…

This early-stage study aimed to understand how eating food and changing the pill's formulation affect how the body absorbs a drug called rilzabrutinib. It involved 24 healthy volunteers who took single doses under different conditions. The main goal was to gather basic safety and…