Pharmacosmos A/s

This study tests if trilaciclib can protect bone marrow in people with limited-stage small cell lung cancer receiving chemotherapy. About 120 participants will get either trilaciclib or a placebo. The goal is to reduce severe low white blood cell counts and other complications fr…

This study tests an intravenous iron medicine (ferric derisomaltose) in 200 children aged 0 to 18 who have iron deficiency anemia due to chronic kidney disease or who cannot take or do not respond to oral iron. The goal is to see if one or two doses can raise hemoglobin levels sa…

This trial tests an oral drug called SP-420 in about 90 adults with transfusion-dependent β-thalassemia or low-risk myelodysplastic syndromes (MDS). The goal is to see how well SP-420 removes excess iron from the liver and other organs, and whether it is safe. Participants take t…

This study tests whether adding trilaciclib before standard chemotherapy (topotecan) can help people with extensive-stage small cell lung cancer live longer. About 302 participants will receive either trilaciclib or a placebo before their chemo, and researchers will compare overa…