Oswaldo Cruz Foundation

This trial tests whether treating hepatitis C in primary care clinics, with non-specialist doctors, works as well as the standard specialist care in Brazil. It also evaluates the use of rapid tests and self-testing to find more people with the infection. The goal is to see if a s…

This study is testing whether weekly WhatsApp messages can help sexual and gender minorities in Brazil stay on track with HIV prevention (PrEP) and treatment (ART). Participants will be randomly assigned to receive either the messages or no messages for six months. The study will…

This study aims to make HIV prevention easier to access for underserved groups in Rio de Janeiro, such as gay and bisexual men, transgender women, and sex workers. Instead of requiring clinic visits, participants can get daily PrEP pills and support through community organization…

This study tests whether taking the antibiotic doxycycline shortly after sex can prevent bacterial STIs like syphilis, gonorrhea, and chlamydia. It involves 200 men, transgender women, and travestis in Rio de Janeiro who are at higher risk. Participants choose whether to use doxy…

This study in Brazil offers young men who have sex with men, transgender, and non-binary people a choice between a daily pill or a twice-yearly injection to prevent HIV. Researchers will follow 1,500 participants for up to two years to see how well each option works in real life,…