Olema Pharmaceuticals, Inc.

This large international study is testing whether a new drug called palazestrant works better than the current standard treatment when combined with another cancer drug called ribociclib. The trial will involve about 1,000 adults with advanced breast cancer that hasn't been treat…

This trial is testing whether a new oral medication called OP-1250 works better than current standard hormone therapies for people with advanced breast cancer that has continued to grow despite previous hormone treatments. The study will enroll about 510 adults whose cancer is ho…

This early-stage study aims to find safe and effective doses for a new breast cancer drug, palazestrant, when combined with four different existing cancer drugs. It will enroll about 190 adults with advanced or metastatic ER-positive, HER2-negative breast cancer who have had limi…

This is the first study in people testing a new oral drug called OP-3136 for advanced or metastatic cancers, including certain types of breast, prostate, and lung cancer. The main goals are to find a safe dose, see how the body processes the drug, and check for early signs that i…