Could a drug for addiction help restless legs sufferers?
Symptom relief
Terminated
This phase 2 trial tests whether d-methadone, a drug related to methadone, can ease symptoms of moderate to very severe restless legs syndrome (RLS). About 50 adults with RLS will take either d-methadone or a placebo daily for 30 days. The goal is to see if it reduces leg discomf…
Phase: PHASE2 • Sponsor: Mauro Manconi • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC